2023年8月26日 · The CSF-VDRL test is done to diagnose syphilis in the brain or spinal cord. Brain and spinal cord involvement is often a sign of late-stage syphilis. Blood screening tests (VDRL and RPR) are better at detecting middle-stage (secondary or latent) syphilis. Normal Results. A negative result is normal. False-negatives can occur.

Quantitative estimation of VDRL is essential in treatment evaluation. CSF VDRL test is very specific for neurosyphilis though its sensitivity is low. Interpretation of VDRL in HIV infection is incompletely understood. Keywords: Prozone phenomenon, syphilis, VDRL.

The Veneral Diseases Research Laboratory (VDRL) assay is a nontreponemal serologic test for syphilis that uses a cardiolipin-cholesterol-lecithin antigen to detect reaginic antibodies. The VDRL test performed on cerebrospinal fluid can be used to diagnose neurosyphilis in patients with a prior history of syphilis infection.

2020年2月24日 · A VDRL test on the CSF typically occurs if a doctor suspects that the syphilis is at a more advanced stage when it can affect the brain and central nervous system. This is called neurosyphilis.

A positive VDRL in a spinal fluid uncontaminated by serum is essentially diagnostic of neurosyphilis; however, a negative test may occur in 30% of patients with tabes dorsalis. The CSF VDRL may take years to become nonreactive after adequate therapy.

2024年4月21日 · The key diagnostic points of early asymptomatic neurosyphilis are the lack of neurological symptoms and the CSF examination demonstrating a positive nontreponemal VDRL test serology. Patients may or may not show evidence of primary or secondary syphilis.

CSF VDRL, neurosyphilis test, neurosyphilis detection test. What is this test? This test looks for signs in your cerebrospinal fluid (CSF) that might mean you have neurosyphilis. Syphilis is a bacterial infection. It's a sexually transmitted infection (STI) that can also be spread from a pregnant woman to her fetus.

The Veneral Diseases Research Laboratory (VDRL) assay is a nontreponemal serologic test for syphilis that uses a cardiolipin-cholesterol-lecithin antigen to detect reaginic antibodies. The VDRL test performed on cerebrospinal fluid can be used to diagnose neurosyphilis in patients with a prior history of syphilis infection.

A reactive CSF-VDRL, free of blood or other contamination almost always indicates past or present CNS syphilis. A biological false positive CSF-VDRL test result for syphilis is rare. The CSF-VDRL syphilis test is not an appropriate screening test …

The CSF-VDRL test is done to diagnose syphilis in the brain or spinal cord. Brain and spinal cord involvement is often a sign of late-stage syphilis. Blood screening tests (VDRL and RPR) are better at detecting middle-stage (secondary or latent) syphilis.