2023年6月2日 · Small heel radii can also lead to increased vial breakage (a so-called “lensing” failure) during processes such as lyophilization. A heel radius that is too large, otherwise …

Heel (Insweep) - The lowest portion of the bottle where the body begins to curve into the base. The heel usually terminates at the resting point of the bottle, i.e., the extreme outer edge of the …

In this study, we show how an ALD coating can act as an extractables and leachables barrier and surface functionalizer for primary packaging glass vials. We assessed the barrier property of a …

2025年2月25日 · In the groups that tested positive for methylene blue staining, all the staining was exclusively found around the heel of the vials. This was anticipated as the heel is known …

Replacement Vial Level 7.5" Heel w/ screws. Comes with all you need to bolt to your 7.5" Fusion Pro

2012年4月1日 · In this work, we demonstrate that differential interference contrast (DIC) microscopy is a powerful, effective, and convenient technique to examine the inner surface …

Boron-containing compounds move around and evaporate as gas out of the glass network largely in the heel region of the vial. Like a charged helium balloon sticks to a wall or object, the boron …

borosilicate vial (vials in this population exhibited delamination) showed quantifiable boron and sodium enrichment of the glass composition (>200% of the bulk value) in the heel area (24 …

2024年9月1日 · The results from Shah et al., Kucko et al., and this study corroborate the impact that autoclaving vials in the upright orientation has on the pH of a drug product due to being in …

2025年2月28日 · For example, a relatively small heel radius (i.e., a relatively sharp-cornered heel) can make a vial more prone to tipping over and to severe damage, cracking, etc. when the vial …