2023年6月15日 · We used MRgFUS to produce small lesions in the thalamic ventral intermediate nucleus (VIM), an important node in the cerebello-thalamo-cortical tremor network, in 13 patients with...

2024年9月27日 · Our study supports the efficacy and safety of MRgFUS VIM thalamotomy for reducing tremor and improving the quality of life in patients with TDPD, offering a less invasive alternative to traditional surgical methods.

The thalamic ventral intermediate nucleus (VIM) can be targeted for treatment of tremor by several procedures, including deep brain stimulation (DBS) and, more recently, MR-guided focused ultrasound (MRgFUS). To date, such targeting has relied ...

Magnetic resonance-guided focused ultrasound (MRgFUS) ablation of the ventral intermediate (Vim) thalamic nucleus is an incisionless treatment for essential tremor (ET). The standard initial targeting method uses an approximate, atlas-based stereotactic approach. We developed a new patient-specific …

MRgFUS is an “incisionless” technique that uses ultrasound from an array of transducers around the skull to induce focal thermal ablation lesions in the brain during an awake outpatient procedure and magnetic resonance imaging (MRI) for target definition, treatment planning, and closed-loop control of energy deposition (2, 3).

OBJECTIVE Thalamotomy of the ventral intermediate nucleus (VIM) is effective in alleviating medication-resistant tremor in patients with essential tremor (ET) and Parkinson's disease (PD). MR-guided focused ultrasound (MRgFUS) is an innovative technology that enables noninvasive thalamotomy via ther …

We performed MRgFUS left-sided Vim thalamotomy for 10 medication-refractory ET patients (8 men and 2 women, aged 67.1±17.5 years, all right-handed). We followed them for 2 years using the clinical rating scale for tremor (CRST) and the quality of …

Unilateral anterior-VIM/VOP and PSA MRgFUS significantly diminished contralateral arm tremor with improvements in arm function, tremor related disability and quality of life, with an acceptable adverse event profile.

Magnetic resonance (MR)-guided focused ultrasound surgery (MRgFUS) is the latest minimally invasive stereotactic procedure, and thalamotomy using this novel modality has demonstrated its effectiveness and safety, especially for patients with essential tremor …

2021年6月29日 · The validity of the DRTT tractography in Vim targeting for tremor treatment was also confirmed using MRgFUS, demonstrating the postoperative evidence of DRTT interruption in patients with...