The current findings advance innovation in drug discovery and highlight C53 as a novel pGC-B activator with sustained in vivo activity and anti-fibrotic actions in vitro. Future studies are warranted to explore the efficacy and therapeutic opportunity of C53 targeting fibrosis in cardiorenal disease states and beyond.

2021年6月9日 · vivo Y53s Android smartphone. Announced Jun 2021. Features 6.58″ display, Snapdragon 480 5G chipset, 5000 mAh battery, 256 GB storage, 8 GB RAM.

2023年5月31日 · Realme C53 Android smartphone. Announced May 2023. Features 6.74″ display, Unisoc Tiger T612 chipset, 5000 mAh battery, 256 GB storage, 8 GB RAM.

What is the difference between Vivo Y17s and Realme C53? Find out which is better and their overall performance in the smartphone ranking.

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Here we established that C53 selectively generates cGMP via the pGC-B receptor and is highly resistant to NEP and has less interaction with NPRC in vitro. Furthermore in vivo, C53 had enhanced cGMP-generating actions that paralleled elevated plasma CNP-like levels, thus indicating a longer circulating half-life compared to CNP.

This is a side-by-side smartphone specs comparison of the vivo Y27 and realme C53. The vivo Y27 has a 6.64-inch display, MediaTek Helio G85 processor, dual cameras, 4G LTE connectivity, and 5000mAh battery. Meanwhile, the realme C53 has a 6.74-inch display, UNISOC Tiger T612 processor, dual cameras, 4G LTE connectivity, and 5000mAh battery.

2024年12月14日 · Vivo C53 ditenagai oleh prosesor Snapdragon 480, RAM 8 GB, dan penyimpanan internal 128 GB. Ponsel ini memiliki baterai berkapasitas 5000 mAh yang mendukung pengisian cepat 33 W. Vivo C53 merupakan ponsel yang terjangkau dengan fitur-fitur yang cukup lengkap.

In our in vivo study using normal rats, we observed that acute IV infusion of C53 generated significantly higher CLL compared to equimolar infusion of CNP. This marked elevation in plasma CLL with C53 was paralleled with significantly elevated levels of plasma and urinary cGMP, the second messenger of pGC-B activation.

What is the difference between Vivo Y28 5G and Realme C53? Find out which is better and their overall performance in the smartphone ranking.