2018年7月1日 · Here, we describe that VPS28, an ESCRT-I component, directly interacts with Gβγ, a signaling heterodimer with documented impact on microtubule dynamics, composing a novel organizer of the mitotic spindle aster. We found that VPS28 localizes to mitotic microtubules where it recruits Gβγ.

2024年12月25日 · VPS28 (VPS28 Subunit Of ESCRT-I) is a Protein Coding gene. Diseases associated with VPS28 include Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis 7. Among its related pathways are Budding and maturation of HIV virion and HIV Life Cycle.

BioGRID Interaction 1195721 Between VPS28 And AKAP11. Toggle navigation. Bio GRID 4.4

2020年10月15日 · Here we show that the ESCRT-I subunits VPS28A and VPS28B are functionally redundant and required for embryonic development in Arabidopsis. We conducted a screen for genetic enhancers of pid, which is defective in auxin signaling and transport.

我们的研究结果表明，Vps28 作为一种细胞间内体调节剂，介导神经元 EV 的分泌，进而与内皮细胞通信，通过 VEGF-A 运输介导血管生成。 Extracellular vesicles (EVs) participate in intercellular communication and contribute to the angiogenesis.

escrt-i 的 vps28 亚基： 该基因编码 escrt-i 复合物 (运输所需的内体复合物) 的蛋白质亚基，其在将蛋白质运输和分类到亚细胞囊泡中发挥作用。 这种复合物也可以被劫持以促进包膜病毒从细胞膜中出芽。

Vps28-CTD mutations abolishing Vps20 interaction in vitro also prevent the rescue of the EIAV Gag late domain mutant consistent with a potential direct Vps28-ESCRT-III Vps20 recruitment. Therefore, the physiological relevant EIAV Gag-Alix interaction can be functionally replaced by a Gag-Vps28-CTD fusion.

在ncp104突变体中，ESCRT-I复合体中VPS28A蛋白的第194位谷氨酸突变为赖氨酸（VPS28 E194K ），导致植株矮小、开花时间晚、叶片小和角果短小等表型。然而，vps28a功能缺失突变体却与野生型类似。

Here we show that the ESCRT-I subunits VPS28A and VPS28B are functionally redundant and required for embryonic development in Arabidopsis. We conducted a screen for genetic enhancers of pid, which is defective in auxin signaling and transport.

Here we show that the ESCRT-I subunits VPS28A and VPS28B are functionally redundant and required for embryonic development in Arabidopsis. We conducted a screen for genetic enhancers of pid, which is defective in auxin signaling and transport.