
Functional characterization of lysosomal interaction of Akt with VRK2
2018年6月5日 · In 293T cells transfected with Akt, VRK2, and Phafin2, we observed Akt interaction with Phafin2 and VRK2, but no interaction between Phafin2 and VRK2 was …
VRK2 promotes colorectal cancer growth and impedes …
VRK2 upregulation predicts poor prognosis in colorectal and 33 other cancers (TCGA/GTEx data). VRK2 deletion suppresses CRC proliferation/migration; overexpression enhances …
Human VRK2 (Vaccinia-related Kinase 2) Modulates Tumor Cell …
Human VRK2 (vaccinia-related kinase 2), a kinase that emerged late in evolution, affects different signaling pathways, and some carcinomas express high levels of VRK2. Invasion by cancer …
VRK2 Inhibits Mitogen-Activated Protein Kinase Signaling and …
2010年8月2日 · Vaccinia-related kinase (VRK) proteins are Ser-Thr kinases that regulate several signal transduction pathways. In this work, we study the effect of VRK2 on MAPK signaling …
VRK2 activates TNFα/NF-κB signaling by phosphorylating IKKβ in ...
The Flag-VRK2 plasmid was transfected into 293T cells. Forty-eight hours later, Flag-VRK2 was purified by coimmunoprecipitation (Co-IP) and competitively eluted with a Flag polypeptide to …
Differential Inhibitor Sensitivity between Human Kinases VRK1 and VRK2 …
Human vaccinia-related kinases (VRK1 and VRK2) are atypical active Ser-Thr kinases implicated in control of cell cycle entry, apoptosis and autophagy, and affect signalling by mitogen …
Substrate profiling of human vaccinia-related kinases identifies …
2011年12月21日 · In this report the substrate specificity of atypical human vaccinia-related kinases (VRK1 and VRK2) using a human peptide-array containing 1080 sequences …
Interaction of VRK family of kinases with Akt in ... - ResearchGate
VRK2 (vaccinia-related kinase 2) is a novel Ser-Thr kinase 23 . VRK2 can interact with phosphorylated AKT after autophagy induction, controlling cellular proliferation and …
Human VRK2 (Vaccinia-related Kinase 2) Modulates Tumor Cell …
2012年12月12日 · Human VRK2 (vaccinia-related kinase 2), a kinase that emerged late in evolution, affects different signaling pathways, and some carcinomas express high levels of …
Functional characterization of lysosomal interaction of Akt with VRK2
2018年6月5日 · In 293T cells transfected with Akt, VRK2, and Phafin2, we observed Akt interaction with Phafin2 and VRK2, but no interaction between Phafin2 and VRK2 was …
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