2024年12月25日 · WNK1 (WNK Lysine Deficient Protein Kinase 1) is a Protein Coding gene. Diseases associated with WNK1 include Pseudohypoaldosteronism, Type Iic and Neuropathy, …

wnk1是一种广泛表达的 丝氨酸苏氨酸激酶 ，高渗透胁迫会使得wnk1从均匀分布转变为点状分布，但是这些点状信号的作用尚不清楚。 通过活体成像，作者们发现瞬时表达大鼠的WNK1在高 …

WNK1 (with no lysine (K)) is a widely expressed serine/threonine protein kinase. The role of this kinase was first described in the kidney where it dynamically controls ion channels that …

The WNK1 gene provides instructions for making multiple versions (isoforms) of the WNK1 protein. The different WNK1 isoforms are important in several functions in the body, including …

WNK (lysine deficient protein kinase 1), also known as WNK1, is an enzyme that is encoded by the WNK1 gene. [5][6][7][8][9] WNK1 is serine-threonine protein kinase and part of the "with …

2025年2月8日 · WNK1 mediates amphiregulin-induced MMP9 expression and cell invasion in human extravillous trophoblast cells. WNK1 controls endosomal trafficking through TRIM27 …

2022年10月31日 · WNK1 is a molecular crowding sensor that undergoes cell shrinkage-dependent phase separation to restore cell volume. This study provides a clear link between …

2022年9月19日 · WNK kinases are involved in the regulation of tumor growth, metastasis and angiogenesis through complex mechanisms. WNK-SPAK/OSR1 signaling is a potential target …

2020年4月14日 · WNK1 and WNK4 activate the NaCl cotransporter (NCC) at the distal convoluted tubule through oxidative stress-responsive gene 1 (OSR1)/Ste20-related …

2025年2月8日 · WNK1 is a dual modulator of TGFbeta-Smad signaling pathways; WNK1 is a physiologically relevant target of insulin signaling through PI3K and Akt/PKB and functions as …