Presence of invasive WPOI is associated with advanced T stage, poor differentiation, PNI, greater depth of invasion, and higher chances of nodal metastasis. WPOI is associated with poor …

2020年12月29日 · Worst pattern of invasion (WPOI) (AJCC: Cancer Staging [Accessed 21 September 2018], CAP: Protocol for the Examination of Specimens from Patients with …

The histologic risk assessment score was composed of the worst pattern of invasion (WPOI), lymphocytic host response (LHR), and perineural invasion (PNI), as previously described 6 …

2024年3月1日 · This study analyses the prognostic significance of worst pattern of invasion (WPOI) in a unique population of pathologically proven node-negative early-stage oral tongue …

2023年1月4日 · The patients with a high WPOI score (defined as <15 cells in an invasive island, single cells, or satellite tumor cells) were associated with higher mortality compared to those …

2018年6月1日 · Univariate and multivariate analyses revealed that a tumor budding score ≥4 is a significant independent predictive factor for the occurrence of occult neck metastasis, which in …

2023年10月18日 · WPOI is predictive of disease free survival in oral cancer. WPOI is described as five patterns - but generally divided into two (prognostic) groups: WPOI 1-4: better …

2023年10月23日 · In a multicenter study involving 311 patients with OSCC, the WPOI was found to be an independent prognostic factor for the OS and DFS rates, indicating its potential value …

2018年4月19日 · All three invasive patterns, the mode of invasion, WPOI, and tumor budding, were found to be significant predictors of 5-year disease-free survival (p<0.01, p = 0.03, and …

Results: Depth of invasion (P = 0.008), WPOI- 4 and 5 (P = 0.033), sCNS (<5 cells) at tumor interface (P = 0.010), high bud count (≥3 buds/40 × hpf) (P = 0.021) and poor LHR (P = 0.019) …