2018年11月8日 · Here we explore the impact of micropolymorphism on peptide antigen presentation by three closely related HLA molecules, HLA-B*57:01, HLA-B*57:03 and HLA …

人類白細胞抗原（英語： Human leukocyte antigen ，缩写： HLA ），是編碼人类的主要组织相容性复合体（MHC）的基因。 其位于 6号染色体 的短臂上（6p21.31），包括一系列紧密连锁 …

HIV control is strongly associated with the expression of human leukocyte antigen (HLA) alleles in HICs. From the HIV protective HLAs described, HLA-B57 is the most frequent in HIC patients. …

2017年9月1日 · We developed a novel hydrolysis probe–based real-time PCR method of HLA-B*57:01 genotyping. Primer and probes were designed based on published sequence …

HLA-B*57 is the HLA allele that has the greatest impact on the viral-load set point and the rate of disease progression in HIV infection (10, 17, 18, 23, 28, 29, 34, 42, 46, 55). However, critically …

Different genetic assays have been developed for HLA-B*57: 01 screening, each with specific sensitivity, turnaround time and assay costs.

2017年11月30日 · Development of the bioinformatics tool LOHHLA allows precise measurement of allele-specific HLA copy number, improves the accuracy in neoantigen prediction, and …

人类白细胞抗原（human leukocyte antigen, HLA）是由HLA基因复合体所编码的产物，定位于第6染色体短臂上。 HLA系人类组织相容性复合体（MHC）的表达产物，是构成移植排斥反应的 …

2018年11月8日 · Immunophenotypic differences between closely related human leukocyte antigen (HLA) alleles have been associated with divergent clinical outcomes in infection, …

HLA-B57 is a host genetic determinant associated with better virus control and slower disease progression in HIV-infected individuals. You might find these chapters and articles relevant to …