2024年12月11日 · Wet macular degeneration is an eye condition that causes blurred vision or reduced central vision. It is a type of age-related macular degeneration where blood vessels leak fluid or blood into part of the retina known as the macula (MAK-u-luh). The macula is responsible for central vision.

According to recent epidemiological data, 2.3% of the population aged over 65 years in Europe is suffering from neovascular (wet) age-related macular degeneration (wAMD), with the disease posing a significant public health problem [1–3]. wAMD is diagnosed less often than dry AMD, yet it accounts for 90% of severe vision loss cases [1, 2].

2023年8月25日 · Affordable, home-monitoring techniques such as usage of an Amsler grid may help decrease the latency between onset of wet age-related macular degeneration and initiation of treatment. This activity describes who is a candidate for a home Amsler grid and reviews how to use the Amsler grid.

The purpose of this article is to present guidelines, compiled by a panel of specialized ophthalmologists in the area of wAMD, and propose commonly accepted therapeutic response criteria and define treatment discontinuation criteria for patients suffering from wAMD treated with anti-VEGF agents.

With the “wet” type of age-related macular degeneration, patients may see a dark spot (or spots) in the center of their vision due to blood or fluid under the macula. Straight lines may look wavy, or bent, because the macula is no longer smooth. Side or “peripheral” vision is rarely affected.

2024年8月11日 · Wet (exudative or neovascular) age-related macular degeneration is the most common cause of visual impairment among older patients in developed countries. Approximately 10% of patients with age-related macular degeneration develop choroidal neovascularization, which is the hallmark of wet age-related macular degeneration.

wAMD is a chronic, progressive disease of the central part of the retina that affects people over the age of 45. A patient with wAMD requires many years of monitoring and treatment. The current, widely-accepted therapy for wAMD consists of repeated intravitreal injections of drugs blocking vascular endothelial growth factor (VEGF) [ 4 ].

wAMD， 湿性年龄相关性黄斑变性 。通俗来讲：湿性年龄相关性黄斑变性会长异常的新生血管，是因为新生血管因子，也就是血管渗漏因子的升高，视网膜才会长异常的新生血管。

2023年5月25日 · 抗vegf药物的出现成为了治疗眼底血管性疾病（包括wamd）的革命性的治疗措施，具有使患者新生血管显著消退、视力提升、眼底微结构明显改善等作用，这一切均表明抗vegf治疗对大部分wamd有效。

Age-related macular degeneration (AMD) is referred to as the leading cause of irreversible visual loss in developed countries, with a profound effect on the quality of life. The neovascular form of AMD is characterized by the formation of subretinal choroidal neovascularization, leading to sudden and severe visual loss [1].