Lost wax Casting is a one kind of iron casting. The Lost wax casting process will give you a nice and smooth surface. We can garuntee the sastification of the products as well.

Manufacturing and sales of “Heat resistant alloy casting steel” and “Abrasion resistant alloy casting steel” by Semi lost-wax investment casting process by make to order.

IKK是一种常见的 转录因子 激活蛋白 [1]，可以被位于 细胞质膜 的 TNF -TNFR复合体、 IL -ILR复合体、活化的 Toll样受体 、 病毒感染 和胞外电离辐射激活。 常见的 炎症因子 (包括IL-α和TNF-α等)都可以参与激活IKK。 NF-κB 由两类 亚基 形成的 异源二聚体，一类亚基包括p65，另一类亚基为p50。 NF-κB未被激活时和 IκB -α形成一个复合物，分布在细胞浆中。 在炎症因子、 生长因子 或 趋化因子 等可以激活IKK的情况下，IκBkinase (IKK)复合物会被NF-κB-inducingkinase磷酸 …

Phospho-IKKα/β (Ser176/180) (16A6) Rabbit mAb detects IKKα only when phosphorylated at Ser176/180 and IKKβ only when phosphorylated at Ser177/181. The antigen sequence used to produce this antibody shares 100% sequence homology with the species listed here, but reactivity has not been tested or confirmed to work by CST.

Wax sachets, sometimes called scent packs, are a great way to add fragrance to small spaces like closets, drawers, or bathrooms—all while doubling as unique, decorative pieces! You can easily...

Inhibitory kappa B kinase beta (IKKβ), known as IKK2, is a key regulatory kinase responsible for the activation of NF-κB through its phosphorylation at Ser177 and Ser181 to promote the phosphorylation of inhibitors of kappa B (IκBs), triggering their ubiquitination and degradation to active the nuclear factor kappa-B (NF-κB) cascade.

2021年1月18日 · Knockout of IKKα decreased c-Myc-activity and increased its T58-phosphorylation, the target site for GSK3β, triggering polyubiquitination and degradation. c-Myc-mutants mimicking IKK-mediated S67/S71-phosphorylation exhibited slower turnover, higher cell proliferation and lower apoptosis, while the opposite was observed for non ...

IKKβ（和IKKγ）对于促炎性信号传导级联（例如由肿瘤坏死因子α（TNFα）或脂多糖（LPS）触发的级联反应）对NF-κB的快速激活至关重要。 相反，IKKα在特定形式的NF-κB的激活中起一定作用，以响应TNF家族成员的子集，并且还可以减弱IKKβ驱动的NF-κB的激活。 此外，IKKα参与角质形成细胞的分化，但是该功能与其激酶活性无关。 几年前，鉴定出两种蛋白激酶，它们分别表现为IKKε或IKK-i和一种分别命名为TBK1（TANK结合激酶），NAK（NF-κB激活激酶） …