
WDXR - Wikipedia
WDXR (1450 AM), along with FM translator W242CX at 96.3, is a radio station licensed to serve Paducah, Kentucky, United States. The station, established in 1957, is currently owned by …
Targeting WDxR motif reprograms immune microenvironment …
2023年3月22日 · Mechanistically, WDR6 targets tumor suppressor UVRAG to the CUL4A-DDB1-ROC1 E3 ubiquitin ligase complex through a unique WDxR motif and promotes its …
96.3 DXR - The Greatest Hits
96.3 DXR is Paducah’s only radio station playing the greatest hits of your life! The songs you know and love from the 70’s and 80’s. You’ll hear The Eagles, The Doobie Brothers, Chicago, …
【仪器科普课堂】EDXRF和WDXRF知多少? - 知乎专栏
根据分光方式的不同,X射线荧光分析可分为 能量色散 和 波长色散 两类,也就是通常所说的 能谱仪 和 波谱仪,缩写为 EDXRF 和 WDXRF。 方法特点. X射线荧光分析法的特点. (1)适应范 …
靶向 WDxR 基序重编程免疫微环境并抑制肝细胞癌进展,EMBO …
2023年3月22日 · 从机制上讲,wdr6 通过独特的 wdxr 基序将肿瘤抑制因子 uvrag 靶向 cul4a-ddb1-roc1 e3 泛素连接酶复合物并促进其降解。 这通过阻断 p65 的自噬降解来上调 TNFα 基因 …
樊祥山/李全海/张志勇团队联合揭示靶向WDxR结构调控肿瘤免疫 …
2023年3月24日 · 肝细胞癌 (hepatocellular carcinoma,HCC) 是一种具有高复发性和高致死性特征的恶性肿瘤,危害着全球各国人民的生命健康,然而目前临床上的治疗效果仍然不尽人意 …
Arabidopsis DDB1-CUL4 ASSOCIATED FACTOR1 forms a nuclear …
The human DDB1-CUL4 ASSOCIATED FACTOR (DCAF) proteins have been reported to interact directly with UV-DAMAGED DNA BINDING PROTEIN1 (DDB1) through the WDxR motif in …
2023年3月22日 · Mechanistically, WDR targets tumor suppressor UVRAG. unique WDxR motif and promotes its degradation. This upregu-lates chromatin accessibility at the TNFa locus by …
Targeting WDxR motif reprograms immune microenvironment …
2023年3月22日 · Mechanistically, WDR6 targets tumor suppressor UVRAG to the CUL4A‐DDB1‐ROC1 E3 ubiquitin ligase complex through a unique WDxR motif and promotes …
The CRL4Cdt2 ubiquitin ligase targets the degradation of p21Cip1 …
2008年9月9日 · In this study, we identified the C. elegans WDXR motif protein CDT-2 as an SRS for a CRL4 E3 complex that targets the CDK inhibitor CKI-1 and the replication-licensing factor …