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2024年11月18日 · The findings suggest that the therapy could be a promising treatment to help prevent premature heart disease in people with high levels of Lp(a), which is estimated to …

Often referred to as Lp (a), lipoprotein (a) is a type of lipoprotein that is genetically inherited and in high levels is a common independent risk factor for heart disease. How common is high Lp …

2023年11月29日 · Lp (a) is a genetically inherited lipoprotein and a common independent risk factor for heart disease. Lp (a) is made up of two major proteins: apolipoprotein (a) [apo (a)] …

2023年2月1日 · About 20% of people have high blood levels of lipoprotein(a)—Lp(a) for short—which can double or triple their risk of a heart attack. With new treatments that can …

2025年1月21日 · All five new drug candidates have been shown to be safe in small early studies and to effectively lower Lp (a) levels. But what the FDA will ultimately look at is whether those …

2023年9月19日 · New lines of therapy targeting lipoprotein (a) (LPA) gene translation are being developed. Lipoprotein (a) (Lp [a]) is a low-density lipoprotein–like molecule with an …

2024年11月18日 · Muvalaplin, an oral, once-daily treatment that inhibits lipoprotein (a) formation via a novel mechanism, achieved positive results in a 12-week Phase 2 study. These data …

2021年7月2日 · Lipoprotein(a) [Lp(a)] is an atherogenic lipoprotein with a strong genetic regulation. Up to 90% of the concentrations are explained by a single gene, the LPA gene. …

2024年6月26日 · There has been substantial progress in understanding the biology and pathophysiology of Lp (a) in the last 6 decades, including its discovery as a unique β …