
Structural basis for the recognition of the bacterial tyrosine kinase ...
2022年6月6日 · The structure of the Wzb–Wzc CDΔC complex determined here not only reveals key structural features that enable molecular recognition between these two species but also …
The molecular basis of regulation of bacterial capsule assembly by Wzc …
2021年7月16日 · Gram-negative species couple polymerization with translocation across the periplasm and outer membrane and the master regulator of the system is the tyrosine …
Rational targeting of Wzb phosphatase and Wzc kinase …
2020年6月1日 · Wzc exhibits auto-phosphorylation protein tyrosine kinase activity, while Wzb is a protein tyrosine phosphatase. Wzb mediates dephosphorylation of Wzc. Dephosphorylated …
Wza gene knockout decreases Acinetobacter baumannii virulence …
Expression levels of wzb, wzc and wzi were decreased in wza knockout strains. The antioxidant capacity of Wza knockout bacteria was only slightly decreased. Complementation of the wza …
wzb磷酸酶和wzc激酶相互作用的合理靶向抑制了 ... - X-MOL
EPS的合成及其输出受细菌Wza-Wzb-Wzc系统的调节。 Wzc表现出自磷酸化蛋白酪氨酸激酶活性,而Wzb是一种蛋白酪氨酸磷酸酶。 Wzb介导Wzc的去磷酸化。
The role of the tyrosine kinase Wzc (Sll0923) and the phosphatase Wzb …
2019年1月23日 · The results obtained demonstrate that Wzc (Sll0923) and Wzb (Sll0328) are involved in the production of EPS, influencing both the amount and the composition of …
Functional Analysis of Conserved Gene Products Involved in …
In this biosynthesis pathway, Wza, Wzb, and Wzc homologues are required for surface expression of wild-type CPS or EPS. Multimeric complexes of Wza in the outer membrane are …
Rational targeting of Wzb phosphatase and Wzc kinase …
EPS synthesis and its export is regulated by the bacterial Wza-Wzb-Wzc system. Wzc exhibits auto-phosphorylation protein tyrosine kinase activity, while Wzb is a protein tyrosine …
Cells of Escherichia coli Contain a Protein-Tyrosine Kinase, Wzc, …
Two proteins of Escherichia coli, termed Wzc and Wzb, were analyzed for their capacity to participate in the reversible phosphorylation of proteins on tyrosine. First, Wzc was …
Structural diversity among Acinetobacter baumannii K-antigens …
Capsular polysaccharide (CPS or K-antigen) is one of the major virulence factors which aids A. baumannii in evading the host immune system. K-antigens of A. baumannii exploit the …
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