2008年12月1日 · There are 3 main patterns of ANCA: cytoplasmic (c-ANCA), perinuclear (p-ANCA), and atypical (x-ANCA). x-ANCA recognizes some inflammatory proteins that could be a potential field of investigation for biologic therapy. Prevalence of x-ANCA in patients with ulcerative colitis (UC) is from 59% to 84% and its utility remains unknown.

Anti-neutrophil cytoplasmic antibodies (ANCAs) are a group of autoantibodies, mainly of the IgG type, against antigens in the cytoplasm of neutrophils (the most common type of white blood cell) and monocytes.

2024年8月31日 · Antineutrophil cytoplasmic antibody (ANCA)–associated vasculitides are a heterogeneous group of rare autoimmune conditions that cause inflammation of blood vessels with various manifestations. The 3 main ANCA–associated vasculitides are granulomatosis with polyangiitis, microscopic polyangiitis, and eosinophilic granulomatosis with polyangiitis.

ANCAs are proteins made by the immune system that mistakenly target neutrophils, infection-fighting white blood cells. ANCA testing helps healthcare providers diagnose and monitor certain types of vasculitis and inflammatory bowel disease. What is an ANCA test?

1996年1月1日 · This chapter focuses on antineutrophil cytoplasmic autoantibodies (X-ANCA) that reacts with neutrophil antigens other than proteinase 3 and myeloperoxidase. Detection of ANCA is a useful laboratory diagnostic test for certain small vessel vasculitides and some nonvasculitic clinical syndromes, such as inflammatory bowel disease (IBD).

Les anticorps anti-cytoplasme des polynucléaires neutrophiles (ANCA) sont des auto-anticorps dirigés contre des antigènes présents dans les granules azurophiles des polynucléaires neutrophiles. Ce sont des marqueurs diagnostiques des vascularites, dont ils ont changé le diagnostic et la classification.

2020年8月24日 · "UC-ANCA" (also called "atypical P-ANCA" or "X-ANCA") is the type of ANCA most commonly found in some patients with certain inflammatory bowel and liver disease, namely, ulcerative colitis (72-80%), primary sclerosing cholangitis (72-80%), and autoimmune hepatitis type 1 (50-80%).

2017年9月15日 · Anti-neutrophil cytoplasmic antibodies (ANCAs) are valuable laboratory markers used for the diagnosis of well-defined types of small-vessel vasculitis, including...

采用间接免疫荧光法(1f了)，可将anca分为胞浆型(c-anca)、核周型(p-anca)和不典型anca(x-anca)。 C—ANCA的靶抗原是髓 过氧化物酶 (myeloperoxidase，MPO)、弹性蛋白酶(elastase)、组织蛋白酶C(cathepsin G)、溶菌酶、乳肝褐素(1actoferrin)，在所有ANCA阳性血清中约占40%。

Anti-neutrophil cytoplasmic antibodies (ANCA) are autoantibodies associated with certain forms of vasculitis, including Wegener’s granulomatosis, micropolyateritis, glomerulonephritis, other vasculitides and inflammatory bowel disorders.