X-linked dystonia parkinsonism (XDP), also known as lubag syndrome or X-linked dystonia of Panay, is a rare X-linked progressive movement disorder with high penetrance found almost exclusively in males from Panay. [1] It is characterized by dystonic movements first typically occurring in the 3rd and 4th decade of life.

XDP is an inherited neurodegenerative movement disorder that changes over the course of many years, resulting in significant disability. Beginning in adulthood, people with XDP experience movement problems, called dystonia or parkinsonism.

XDP in Medical commonly refers to X-linked Dystonia-Parkinsonism, a rare neurological condition characterized by a combination of movement disorders, including dystonia and parkinsonism, primarily affecting individuals of Filipino descent. This condition is caused by mutations in the DYT3 gene on the X chromosome.

X-linked dystonia-parkinsonism (XDP) is a neurodegenerative movement disorder characterized by adult-onset parkinsonism that is frequently accompanied by focal dystonia, which becomes generalized over time, and that has a highly variable clinical course.

2005年12月13日 · Individuals with X-linked dystonia-parkinsonism (XDP) have dystonia of varying severity and parkinsonism. XDP afflicts primarily Filipino men and, rarely, women. The mean age of onset in men is 39 years; the clinical course is highly variable with parkinsonism as the initial presenting sign, overshadowed by dystonia as the disease progresses.

What is X-linked Dystonia-Parkinsonism (XDP)? X-Linked Dystonia Parkinsonism, also called Lubag or DYT3 dystonia, primarily affects men with Filipino ancestry from the Island of Panay. XDP is an inherited neurodegenerative movement disorder that changes over the course of many years, resulting in significant disability.

X-linked dystonia-parkinsonism (XDP) is a genetic form of dystonia that includes symptoms of both dystonia and parkinsonism. XDP affects males of Filipino descent almost exclusively. Treatment may include physical therapy, oral medications, and botulinum toxin injections.

X-Linked Dystonia Parkinsonism (XDP) is indexed as a /DYT3/ dystonia, and also becoming known worldwide as “Lubag.” First described in a published work by Lee in 1976,1 XDP is a progressive neurodegenerative disease affecting mainly male Filipinos, whose maternal ancestries originate from the Philippine island of Panay. XDP usually starts ...

Introduction: X-linked dystonia-parkinsonism (XDP) is a progressive neurodegenerative disorder that has been studied well in recent years. Objectives: This scoping review aimed to describe the current state of knowledge about the diagnosis and treatment of XDP, to provide clinicians with a concise and up-to-date overview.

X-linked dystonia-parkinsonism (XDP) is an adult-onset neurodegenerative movement disorder, caused by a founder retrotransposon insertion in an intron of the TAF1 gene.