2024年5月23日 · XDR-TB, an abbreviation for extensively drug-resistant tuberculosis (TB), is a form of TB that is caused by a strain of M. tuberculosis complex that is resistant to rifampicin (and may also be resistant to isoniazid), and that is also resistant to at least one fluoroquinolone (levofloxacin or moxifloxacin) and to at least one other Group A drug ...

2023年12月21日 · Multidrug-resistant TB disease (MDR TB) is caused by germs that are resistant to two or more of the main TB medicines: isoniazid and rifampin. Two more serious forms of MDR TB are called pre-extensively drug-resistant TB (pre-XDR TB) …

Extensively drug-resistant tuberculosis (XDR-TB) is a form of tuberculosis caused by bacteria that are resistant to some of the most effective anti-TB drugs. XDR-TB strains have arisen after the mismanagement of individuals with multidrug-resistant TB (MDR-TB).

2021年1月27日 · The definition of extensively drug-resistant tuberculosis (XDR-TB) has been revised by the World Health Organization (WHO)’s Global TB Programme, who have also defined pre-XDR-TB for the first time, highlighting the seriousness of these forms of TB.

2025年1月6日 · Pre-extensively drug-resistant TB (pre-XDR TB) disease is a type of MDR TB caused by TB bacteria that are resistant to: Isoniazid, rifampin, and a fluoroquinolone or Isoniazid, rifampin, and a second-line injectable (amikacin, capreomycin, and kanamycin).

2024年12月30日 · In TB-PRACTECAL (19), people receiving BPaL (n = 60) for 24 weeks, including linezolid initiated at 600 mg for MDR-/RR- or pre-XDR-TB, had a higher success rate than persons receiving SoC (n = 66) regimens (77% vs. 52%) and fewer grades 3 to 5 adverse events (20% vs. 51%) (Tables 7 and E3).

Extensively drug resistant TB (XDR TB) is a rare type of multidrug-resistant tuberculosis (MDR TB) that is resistant to isoniazid and rifampin, plus any fluoroquinolone and at least one of three injectable second-line drugs (i.e., amikacin, kanamycin, or capreomycin).

Extensively drug-resistant TB (XDR-TB) is a form of TB that is resistant to at least four of the core anti-TB drugs. XDR-TB involves resistance to the two most powerful anti-TB drugs, namely isoniazid and rifampicin.

2021年2月1日 · New definitions for pre-XDR and XDR-TB will help to define more precisely groups of TB patients who require complex treatment regimens. These new definitions are also expected to lead to better...

Extensively drug-resistant tuberculosis (XDR-TB) is an even more severe form of drug resistant TB than multidrug-resistant TB (MDR-TB). In 2006, the first reports of XDR-TB began to appear. [1,2] MDR-TB is defined as resistance to isoniazid and rifampicin, with or without resistance to other first-line drugs (FLD).