DNA repair protein XRCC1, also known as X-ray repair cross-complementing protein 1, is a protein that in humans is encoded by the XRCC1 gene. XRCC1 is involved in DNA repair, …

2024年12月25日 · XRCC1 (X-Ray Repair Cross Complementing 1) is a Protein Coding gene. Diseases associated with XRCC1 include Spinocerebellar Ataxia, Autosomal Recessive 26 …

Human X-ray repair cross complementing gene 1 (XRCC1) is the first mammalian gene found to affect cell sensitivity to ionizing radiation, and plays an important role in regulating DNA sin-gle …

XRCC1 is a molecular scaffold protein that interacts with multiple enzymatic components of DNA single-strand break repair (SSBR) including DNA kinase, DNA phosphatase, DNA …

XRCC1 protects transcription from toxic PARP1 activity during DNA base excision repair. X-ray repair cross-complementing protein 1 (XRCC1) loss promotes beta-lapachone -induced …

2021年11月22日 · We show that aberrant PARP1 activity suppresses transcriptional recovery during base excision repair by promoting excessive recruitment and activity of the ubiquitin …

2019年9月1日 · XRCC1 is a molecular scaffold protein that interacts with multiple enzymatic components of DNA single-strand break repair (SSBR) including DNA kinase, DNA …

该蛋白与 DNA 连接酶 III、聚合酶 β 和聚 (ADP-核糖) 聚合酶相互作用，参与碱基切除修复途径。 它可能在生殖细胞减数分裂和重组过程中的 DNA 加工中发挥作用。 该基因中罕见的微卫星多 …

X-ray cross complementing group 1 protein (XRCC1) forms enzyme complexes optimized for single-strand break repair, but participates in other repair pathways as well. Available …

2022年5月20日 · x射线修复交叉互补蛋白1（xrcc1）是碱基切除修复和单链断裂修复通路中重要的支架蛋白。 研究基于近代物理所高能微束装置的在线活细胞成像系统，探究了多种重离子辐 …