Klinefelter syndrome (KS), also known as 47,XXY, is a chromosome anomaly where a male has an extra X chromosome. [10] These complications commonly include infertility and small, poorly functioning testicles (if present).

克氏症候群（英語： Klinefelter's syndrome ）或称XXY、47XXY症候群，俗称次雄性症候群，是由於男性有两条或两条以上的X染色体所致的疾病。 该疾病的主要特徵為 不育 [ 1 ] 。

Oct 29, 2024 · One extra copy of the X sex chromosome in each cell (XXY), the most common cause. An extra X sex chromosome in some of the cells. This is called mosaic Klinefelter syndrome and may result in fewer symptoms. More than one extra copy of the X sex chromosome, which is rare and results in a severe form of the syndrome.

常见染色体核型为：47，xxy， 嵌合型：46，xy/47，xxy。 其原因是精子或卵子在生长发育过程中，X染色体不分离所致。 克氏综合征患者由于存在一条额外的X染色体，往往存在男性 性腺功能低下 、雄激素不足、 生精功能受损 等问题。

Oct 28, 2024 · Klinefelter syndrome, also known as XXY syndrome, is a condition in boys and men that’s caused by an extra X chromosome. It can affect physical and mental development.

Klinefelter syndrome, also called 47,XXY, is a chromosomal condition that affects male development. The signs and symptoms of Klinefelter syndrome vary. In some cases, the features are so mild that the condition is not diagnosed until puberty or adulthood.

This includes one copy of an X chromosome and one copy of a Y chromosome (46, XY). People with Klinefelter syndrome have a total of 47 chromosomes (47, XXY).

Mar 4, 2025 · XXY syndrome is the most common sex chromosome disorder among humans and affects approximately 1 in 500 to 1,000 genetic males. What causes XXY syndrome? XXY syndrome may be caused by a random error that occurs during meiosis (i.e., the process of producing gametes or sex cells) and therefore, is not inherited from parents.

Most men are born with a pair of XY chromosomes, while most females are born with pair of XX chromosomes. Klinefelter syndrome occurs when a male is born with an extra X chromosome. Thus a male with Klinefelter has XXY instead of the usual XY pair.

Living with XXY is changing the way the world learns about Klinefelter syndrome/47 XXY. Focusing on community, awareness, and positive traits.