
Methoxy-X04 | 荧光染料 - MCE
Methoxy-X04 is a fluorescent dye that crosses the blood-brain barrier and selectively binds to beta-pleated sheets found in dense core amyloid Aβ plaques. Methoxy-X04 retains in vitro …
Methoxy-X04 甲氧基X04 (淀粉样蛋白β荧光探针) - 上海懋康生 …
甲氧基X04(Methoxy-X04),作为刚果红和柯胺G的衍生物,是一种具血脑屏障渗透性的淀粉样蛋白β(Aβ)荧光探针,用来检测和定量淀粉样斑块、缠结和脑血管淀粉样蛋白。 体外,甲氧 …
甲氧基-X04;β 淀粉样蛋白荧光标记物 - 知乎 - 知乎专栏
Methoxy-X04 (甲氧基 -X04)是一种荧光 淀粉样蛋白 β (Aβ) 探针,Methoxy-X04 用于检测和量化斑块、缠结和脑血管淀粉样蛋白。 显示高体外结合亲和力(Ki = 26.8 nM); 选择性地与纤维 …
阿尔茨海默病中噬斑小胶质细胞的基因特征被发现
2021年5月25日 · 研究小组使用了一种叫做甲氧基-XO4(methoxy-XO4)的染色剂,这种染色剂专门针对吞噬淀粉样斑块的小胶质细胞。 他们将这种染色剂用于阿尔茨海默病的临床前模型, …
Methoxy-X04 | Fluorescent Amyloid B Probes: R&D Systems
Key information: Methoxy-X04 is a blood-brain barrier penetrant fluorescent amyloid β (Aβ) probe. Suitable for in vivo imaging. Used for: the detection and quantification of Aβ plaques, tangles …
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Methoxy-X04 | Aβ fluorescent probe | CAS NO.:863918-78-9
Methoxy-X04 is a fluorescent derivative of Congo Red and Thioflavin T, lacking acidic groups, with a smaller molecular weight and increased lipophilicity. Methoxy-X04 can cross the blood …
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Methoxy-X04, amyloid beta fluorescent marker - Abcam
Blood-brain barrier permeable amyloid β fluorescent marker. Blue fluorophore. Derivative of Congo Red (ab145645) and Chrysamine G. Selectively binds fibrillar β-sheet deposits with …
Nat Commun:科学家发现阿尔兹海默病发病过程中负责摄入淀粉样斑块的小胶质细胞的关键基因特征
研究人员通过使用一种名为甲氧基-XO4的染色剂做到了这一点,该染色剂能专门靶向作用吞噬淀粉样斑块的小胶质细胞。 研究人员在阿尔兹海默病临床前模型研究中使用了这种染色剂,随后 …
美国APExBIO中文官网 - Methoxy-X04
Methoxy-X04, a derivative of Congo red and Chrysamine-G, is a brain-permeable fluorescent probe for amyloid-β (Aβ) [1]. Aβ peptides, proposed as a cause of Alzheimer’s disease, exists …
Methoxy-X04 (CAS 863918-78-9) - Cayman Chem
Methoxy-X04 is a brain-permeable fluorescent probe for amyloid-β (Aβ) to detect and quantify plaques, tangles, and cerebrovascular amyloid. 1 It displays high in vitro binding affinity (K i = …