Evidence for discrete modes of YAP1 signaling via mRNA splice isoforms ...
2021年5月1日 · Yes-associated protein 1 (YAP1) is a transcriptional co-activator downstream of Hippo pathway. The pathway exerts crucial roles in organogenesis and its dysregulation is …
Yeast AP-1 like transcription factors (Yap) and stress response: a ...
Yap1 is a direct regulator of ROX1, which in turn represses FET4 . Yap1 also plays an important role in arsenic compound detoxification by regulating genes encoding several of the cellular …
YAP1 - Wikipedia
YAP1 (yes-associated protein 1), also known as YAP or YAP65, is a protein that acts as a transcription coregulator that promotes transcription of genes involved in cellular proliferation …
yap1促进nsclc的增殖、侵袭及转移，促进了nsclc肿 瘤干细胞的更新及血管拟态，降低了NSCLC对化疗、放疗、表皮生长因子受体-酪氨酸激酶抑制剂（epidermalgrouthfactorrecep⁃
癌蛋白YAP1的研究进展 - pibb.ac.cn
Yes相关蛋白1 (Yes-associated protein 1，YAP1)是Hippo信号通路 (Hippo pathway)中的一个分子．早期研究人员发现，在Hippo信号通路正常的情况下，YAP1处于非激活状态；当Hippo信号 …
YAP1 is a key regulator of EWS::FLI1-dependent malignant …
2025年3月12日 · We report that transient exposure to IGF-1 concentrations mimicking serum levels during puberty reprograms limb-derived mesenchymal cells of EWS::FLI1 -mutant mice …
【cell子刊】小分子共价修饰导致TEAD⋅Yap蛋白-蛋白质相互作用的 …
Yap1通过大的扁平界面与TEAD4紧密结合，这使得小分子正构抑制剂的开发极具挑战性。 在此，我们报道了小分子TEAD·Yap抑制剂，该抑制剂可与位于TEADs独特的深层 疏水性棕榈酸 …
YAP1 Gene - GeneCards | YAP1 Protein | YAP1 Antibody
2024年12月25日 · YAP1 (Yes1 Associated Transcriptional Regulator) is a Protein Coding gene. Diseases associated with YAP1 include Coloboma, Ocular, With Or Without Hearing …
Gene: YAP1 (ENSG00000137693) - Summary - Homo_sapiens
This gene has 9 transcripts (splice variants), 1 paralogue and is associated with 4 phenotypes. A single transcript chosen for a gene which is the most conserved, most highly expressed, has …
<br>YAP1-TEAD1-Glut1 轴通过调节糖酵解来决定乳腺癌细胞的致 …
YAP1 的敲除抑制了乳腺癌细胞的细胞外酸化率、葡萄糖消耗和乳酸产生。此外，YAP1 与 TEAD1 相互作用，发挥其对功能靶标葡萄糖转运蛋白 1 (Glut1) 的转录控制。 Glut1 的过度表达恢复 …