免疫受体酪氨酸活化基序 - 维基百科，自由的百科全书
免疫受体酪氨酸活化基序 （英語： immunoreceptor tyrosine-based activation motif，缩写 ITAM）是一个由十多个 氨基酸 构成的保守序列，常出现在 免疫系统 某些细胞的 跨膜蛋白 的 …
Immunoreceptor tyrosine-based activation motif - Wikipedia
An immunoreceptor tyrosine-based activation motif (ITAM) is a conserved sequence of four amino acids that is repeated twice in the cytoplasmic tails of non-catalytic tyrosine-phosphorylated …
ITAM - 百度百科
生物学中，ITAM是免疫受体酪氨酸激活基序（Immunoreceptor tyrosine-based activation motif）的英文缩写，基本组成是：YXXL/V，活化受体与相应配体结合后，在细胞膜相连的一 …
Spatial requirements for ITAM signaling in an intracellular natural ...
2022年11月1日 · Clustering of the ITAMS of FcγRIIIa-FcεRIγ complexes leads to phosphorylation by Lck and subsequent Syk activity. Syk may bind two pYs within a single ITAM in tandem or …
The many faces of ITAMs: Trends in Immunology - Cell Press
In the immune system and beyond, signals transduced through cytoplasmic immunoreceptor tyrosine-based activation motifs (ITAMs) control a variety of key cellular responses, including …
basic-9-ITAM - 知乎 - 知乎专栏
ITAM是一种由6-8个氨基酸残基组成的保守肽段，其序列为Yxx (L/I)x (6-8)Yxx (L/I)。 其中，x表示任意氨基酸残基，而Y表示酪氨酸残基。 ITAM通常存在于细胞膜受体的胞外区域，其结构由 …
The Expanding Role for ITAM-Based Signaling Pathways in …
The immunoreceptor tyrosine-based activation motif (ITAM) is the primary signaling domain used by classical immunoreceptors, such as the antigen receptors on B and T lymphocytes and the …
ITAM-mediated Signaling by the T-Cell Antigen Receptor - PMC
ITAMs, which were identified 20 years ago on the basis of their sequence homology (Reth 1989), consist of paired YxxL/I motifs separated by a defined interval (YxxL/I-X 6-8 -YXXL/I). In …
A role for the ITAM signaling module in specifying cytokine
2014年3月9日 · Immunoreceptor tyrosine-based activation motifs (ITAMs) and ITAM-like adaptors are some of the most widely used conserved signaling modules in leukocytes 1.
血小板 ITAM 信号对炎症中的血管完整性至关重要 ... - X-MOL
血小板在炎症期间维持血管完整性方面起着关键作用，但对潜在的分子机制知之甚少。 在这里我们报告血小板免疫受体酪氨酸激活基序 (ITAM) 信号，但不是 GPCR 信号，对于预防炎症引起的 …