‪University of California, Berkeley‬ - ‪‪Cited by 478‬‬ - ‪Pharmaceutics‬ - ‪Polymer Chemistry‬ - ‪antibody conjugate‬

2015年7月15日 · Many synthetic strategies are available for preparing well-defined conjugates of peptides/proteins and polymers. Most reports on this topic involve coupling methoxy poly (ethylene glycol) to therapeutic proteins, a process referred to as PEGylation, to increase their circulation lifetime and reduce their immunogenicity.

Affiliations: [Changchun Institute of Posts and Telecommunications, Changchun, China].

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2025年3月9日 · Antibody-drug conjugates (ADCs) have emerged as a rapidly expanding class of therapeutics driven by their superior specificity and clinical efficacy. 14 out of 16 commercially approved ADCs are formulated as lyophilized forms because ADC is generally considered to be less stable than unmodified antibody.

Yuhui Gong MSc in Polymer Chemistry, Wuhan University Born on 13th January, 1988 Citizen of China Accepted on the recommendation of Prof. Dr. Jean-Christophe Leroux (examiner) Prof. Dr. Bruno Gander (co-examiner) Prof. Dr. Marc A. Gauthier (co …

Employing a Surface Tensiometer and a Drop Shape Analyzer to ascertain surface tension, surface energy, and contact angle measurements, this study incorporated results from lyophilization processes as well and discerned that the degree of fogging is directly proportional to the increase in surface energy and inversely related to surface tension.