UniProt is the world's leading high-quality, comprehensive and freely accessible resource of protein sequence and functional information.

2018年11月26日 · Bacillus subtilis possesses four lipoteichoic acid synthases LtaS, YfnI, YvgJ and YqgS involved in the synthesis of cell wall. The crystal structure of the extracellular domain of LtaS revealed a...

Four LtaS orthologues, LtaS BS, YfnI, YqgS and YvgJ, are present in Bacillus subtilis. Using an in vitro enzyme assay, we determined that all four proteins are Mn 2+ -dependent metal enzymes that use phosphatidylglycerol as a substrate.

2018年11月26日 · Bacillus subtilis possesses four lipoteichoic acid synthases LtaS, YfnI, YvgJ and YqgS involved in the synthesis of cell wall. The crystal structure of the extracellular domain of LtaS revealed a phosphorylated threonine and YfnI was identified in two independent phosphoproteome studies. Here, we sh …

[PDB|2W5Q] ([protein|418900B6DBDF3EF300C930B0C75E31B939F3CE00|LtaS] from S. aureus, corresponds to aa 215 ... 615 of [protein|880C655DC7149F6EDC21BD2CF8F9F2C9FBEB2CDB ...

2010年11月23日 · Although B. subtilis YvgJ has been determined to be an LTA primase, dissecting the specific functions of the other three paralogous LtaS in B. subtilis is also of interest. The first insights into the apparent redundancy of these three LtaS in B. subtilis came from elegant studies by Schirner et al .

Lipoteichoic acid (LTA) is an important cell envelope component of Gram-positive bacteria. Bacillus subtilis has four homologous genes for LTA synthesis: ltaS (yflE), yfnI, yqgS and yvgJ. The products LtaS (YflE), YfnI and YqgS are bona fide LTA synthetases, whereas YvgJ functions only as an LTA pri …

We show that LtaS BS, YfnI and YqgS can produce polymers, suggesting that these three proteins are bona-fide LTA synthases while YvgJ functions as an LTA primase, as indicated by the accumulation of a GroP-Glc 2 -DAG glycolipid.

Four LtaS orthologues, LtaS(BS) , YfnI, YqgS and YvgJ, are present in Bacillus subtilis. Using an in vitro enzyme assay, we determined that all four proteins are Mn(2+) -dependent metal enzymes that use phosphatidylglycerol as a substrate.

Explore the novel features of the upcoming release of in its beta version, SubtiWiki v5! It features genomic conservation, interaction of proteins with metabolites, dedicated metabolite pages, and much more! Check the pages for MntRand manganese! yvgJ. 168. lipoteichoic acid synthesis primase. locus. BSU_33360. Molecular weight. 70.57 kDa. pI. 5.31