Three US patents (U.S. Pat. Nos. 4,305,502, 4,371,516, and 5,738,875) assigned to R. P. Scherer discloses Zydis technology based on freeze-drying, which is used to manufacture rapidly...

Zydis (registered trademark) technology is known as a manufacturing technology for such a tablet having extremely high disintegration property in the oral cavity, that is, “ultra-fast...

In December, 1996, the Food and Drug Administration approved Claritin (loratadine) RediTabs from Schering-Plough, the first prescription drug with Zydis technology sold in the U.S. [5] A Zydis tablet is produced by lyophilizing or freeze-drying the drug in a matrix usually consisting of gelatin.

The lyophilization process described in WO 95/23600 is based on the Zydis® technology (Catalent). To create an orally disintegrating tablet using the Zydis® technology, the drug is...

Catalent Pharma has the patent for Zydis technology and best known of the fast dissolving/ disintegrating tablet preparations, was the first marketed new technology tablet. This is a unique freeze dried tablet in which drug is physically entrapped or dissolved within the matrix of fast dissolving carrier material.

Sep 26, 2023 · Under the terms of the agreement, Melt Pharmaceuticals will utilize Catalent’s proprietary Zydis® orally disintegrating tablet (ODT) fast-dissolve technology with MELT-300, a sublingual, needle- and opioid-free patented formulation for procedural sedation during cataract surgery in the U.S. and any other countries mutually agreed upon by ...

Jan 1, 2014 · The Zydis lyophilization technology provided the first approved ODT in the United States in 1996. The earliest US regulatory definition for an ODT reflected the lyophilized ODTs that prevailed...

Apr 23, 2024 · The patent utilizes Zydis® technology to develop oral solid dosage form of Rimegepant that disperses almost instantly in mouth. There are disadvantages in developing ODT using Zydis® technology in terms of production, storage and transport.

Nov 18, 2021 · Patent number: 11077067 Abstract: Provided are pharmaceutical compositions and methods for preparing pharmaceutical compositions comprising Ibuprofen using solventless mixing methods. Excess coating material that is not bound to coated Ibuprofen may be removed by a sieving process.

The Zydis® ODT (orally dissolving tablet) fast-dissolve formulation, is a unique, freeze-dried oral solid dosage form that disperses almost instantly in the mouth – no water required. With more than 20 products launched in 60 countries, it continues to …