NCBI has developed AMRFinderPlus, a tool that identifies AMR genes, resistance-associated point mutations, and select other classes of genes using protein annotations and/or assembled nucleotide sequence.

Welcome to the NCBI National Database of Antibiotic Resistant Organisms (NDARO), a collaborative, cross-agency, centralized hub for researchers to access AMR data to facilitate real-time surveillance of pathogenic organisms.

2019年3月18日 · 抗微生物药物耐药性 (antimicrobial resistance)指微生物（如细菌、病毒和某些寄生虫）阻止抗微生物药物（如抗生素、抗病毒药物和抗疟药物）对其产生作用的能力，致使标准治疗方法失去效力，感染持续存在并可能传播给他人。 参考： https://www.who.int/antimicrobial-resistance/zh/ 日常生活中我们可能大多听说过抗生素耐药性，由于抗生素的过度使用或其他原 …

The CARD is a rigorously curated collection of characterized, peer-reviewed resistance determinants and associated antibiotics, organized by the Antibiotic Resistance Ontology (ARO) and AMR gene detection models.

Antimicrobial resistance (AMR or AR) occurs when microbes evolve mechanisms that protect them from antimicrobials, which are drugs used to treat infections. [2] This resistance affects all classes of microbes, including bacteria (antibiotic resistance), viruses (antiviral resistance), parasites (antiparasitic resistance), and fungi (antifungal ...

It integrates pathogen metadata, links to SNP clusters for genetically related isolates, and antimicrobial resistance genotypes and phenotypes, allowing users to browse and search over 300,000 pathogen isolates, effectively and efficiently providing access to the National Database of Antibiotic Resistant Organisms.

The database contains over 627 AMR HMMs, 6,428 genes, and 682 mutations, placing this data in a hierarchical framework of gene families, symbols, and names in collaboration with multiple groups. The genes in the database consist of 5588 AMR genes, 210 stress response genes, and 630 virulence genes.

This software and the accompanying database are designed to find acquired antimicrobial resistance genes and point mutations in protein and/or assembled nucleotide sequences. We have also added "plus" stress, heat, and biocide resistance and virulence factors for …

2024年1月23日 · AMR gene content can be assessed from whole genome sequencing to detect known resistance mechanisms and potentially identify novel mechanisms.

AMR genes refer to the genes implicated in or associated with the resistance to one or more antibiotics. The resistance may result from the presence or absence of a gene or specific mutions acquired spontaniously or through evolution over time.