Antiviral treatment of cytomegalovirus infection - PubMed
Cytomegalovirus (CMV) is an opportunistic pathogen associated with significant morbidity and mortality in immunocompromised hosts. Antiviral agents specifically targeting CMV were …
Cytomegalovirus (CMV) Treatment & Management: Medical Care ... - Medscape
Letermovir is an anti-CMV drug that was approved by the FDA in November 2017. It inhibits the CMV DNA terminase complex (pUL51, pUL56, and pUL89), which is required for viral DNA...
Anti-CMV therapy, what next? A systematic review - PubMed
2023年11月20日 · The efficacy of anti-CMV immunoglobulins are discussed in CMV congenital infection and in association with direct antiviral therapy in heart transplanted patients. All …
Current and Emerging Antiviral Agents in the Prevention and …
2024年2月28日 · Newer antiviral medications are reshaping the landscape for prevention and treatment of CMV DNAemia, infection, and disease. Letermovir is approved for CMV …
Oral antiviral drugs for treatment of cytomegalovirus in transplant ...
Oral maribavir has demonstrated superior efficacy and safety over CMV DNA polymerase inhibitors for the treatment of refractory or resistant CMV infection. Transplant patients with …
Current and Emerging Antivirals for the Treatment of …
This review provides an overview of disease etiology, existing anti-CMV drugs, advances in emerging therapeutics in clinical development and related recent patents for the treatment of …
Antiviral therapy for human cytomegalovirus - Human …
GCV triphosphate is a potent inhibitor of CMV DNA polymerase and has a long intracellular half-life. Selectivity for virus-infected cells is achieved both by UL97 activation and because GCV …
New Perspectives on Antimicrobial Agents: Maribavir - PMC
Maribavir is an orally bioavailable benzimidazole riboside with potent and selective multimodal anti-CMV activity (23 – 27). Unlike traditional anti-CMV agents which inhibit CMV DNA …
Comparable anti-CMV responses of transplant donor and third-party CMV ...
2022年1月11日 · Our data confirmed that adoptive therapy with third-party or transplant donor CMV-CTLs triggered comparable antiviral responses to CMV infection that might be mediated …
List of 9 CMV Prophylaxis Medications Compared - Drugs.com
Compare risks and benefits of common medications used for CMV Prophylaxis. Find the most popular drugs, view ratings and user reviews.