Adipose triglyceride lipase, also known as patatin-like phospholipase domain-containing protein 2 and ATGL, is an enzyme that in humans is encoded by the PNPLA2 gene. [5] [6] [7] ATGL …

Adipose triglyceride lipase (ATGL) is the key-enzyme for the release of fatty acids (FAs) from triacylglycerol (TG) stores during intracellular lipolysis and produces FAs used for energy …

2022年6月8日 · Here we identified adipose triglyceride lipase (ATGL, also known as patatin-like phospholipase domain containing 2 (PNPLA2)) as a candidate biosynthetic enzyme for …

Adipose triglyceride lipase (ATGL) is the key-enzyme for the release of fatty acids (FAs) from triacylglycerol (TG) stores during intracellular lipolysis producing FAs used for energy …

ATGL initiates the hydrolysis of TGs to release fatty acids (FAs) that are crucial energy substrates, precursors for the synthesis of membrane lipids, and ligands of nuclear receptors. …

Adipose triglyceride lipase (ATGL) is the rate-limiting enzyme of lipolysis. ATGL specifically hydrolyzes triacylglycerols (TGs), thereby generating diacylglycerols and free fatty acids. …

2019年11月22日 · The discovery of adipose triglyceride lipase (ATGL) as a triglyceride lipase provided a heightened understanding of the mechanisms governing mobilization of fat …

The enzyme adipose triglyceride lipase (ATGL) catalyzes the initial and often rate-limiting step of intracellular lipolysis [11]. This involves the conversion of a triacylglycerol molecule to …

3 天之前 · Adipose triglyceride lipase (ATGL), the rate-limiting enzyme for TG hydrolysis, is another critical regulator of lipid turnover [12]. Loss of ATGL function leads to steatosis, while …

2025年3月10日 · ATGL serves as a pivotal enzyme in the balance of lipid synthesis and degradation, influencing cellular energy stores and systemic metabolic health. By liberating …