2024年6月1日 · Basic helix-loop-helices (bHLHs) are present in all eukaryotes and form one of the largest families of transcription factors (TFs) found in plants. bHLHs function as transcriptional activators and/or repressors of genes involved in key processes involved in plant growth and development in interaction with the environment (e.g., stomata and root ...

2023年7月5日 · We set out to address how different classes of bHLH TFs, MYC-MAX and CLOCK-BMAL1, together with an unrelated TF, OCT4, structurally and functionally interact with nucleosomes.

bHLH (basic helix-loop-helix) 转录因子是一种普遍存在于动植物中的转录因子家族, 是植物中最大的转录因子家族之一, 具有重要的生物学功能。 1 bHLH 转录因子的结构及分类bHLH转录因子是一类含有basic helix-loop…

bHLH转录因子，即碱性螺旋—环—螺旋（basic helix-loop-helix，bHLH）蛋白，是广泛存在于植物、动物和真菌中的转录因子超家族之一。bHLH超家族成员含有2个高度保守且功能不同的结构域：碱性区域（basic region）和螺旋—环—螺旋（helix-loop-helix，HLH）区域。

2023年2月15日 · Here, we summarize the structure, classification and regulation of bHLH TFs, and focused on the function and regulatory mechanisms of key bHLH TFs in the abiotic stress response of horticultural crops.

2016年12月7日 · Here, we first discuss the bHLH TFs involved in all kinds of JA-modulated processes in the model plant Arabidopsis thaliana. Secondly, we elaborate on the identity and role of bHLH TFs in the conserved JA-mediated elicitation of …

2021年7月1日 · The basic helix-loop-helix (bHLH) transcription factor family is one of the largest transcription factor gene families in Arabidopsis thaliana, and contains a bHLH motif that is highly conserved throughout eukaryotic organisms. Members of this family have two conserved motifs, a basic DNA binding re …

In this review, we describe how all these mechanisms have a role and crosstalk in one specific family of TFs, the basic helix-loop-helix (bHLH), with a very conserved DNA binding domain and a similar DNA preferred motif, the E-box.

2024年1月22日 · Here, we demonstrate how “Coordinator,” a long DNA motif composed of common motifs bound by many basic helix-loop-helix (bHLH) and homeodomain (HD) TFs, uniquely defines the regulatory regions of embryonic face and limb mesenchyme.

2021年11月16日 · Basic helix-loop-helix (bHLH) transcription factors (TFs) are one of the largest gene families in plants. They regulate gene expression through interactions with specific motifs in target genes. bHLH TFs are not only universally involved in plant growth but also play an important role in plant responses to abiotic stress.