2021年11月23日 · In this Review, we summarize recent reports showing endogenous sources of dsRNA (self dsRNA) and cellular responses that result from activation of dsRNA sensors by …

Double-stranded RNA (dsRNA) is associated with most viral infections - it either constitutes the viral genome (in the case of dsRNA viruses) or is generated in host cells during viral replication.

Double-stranded RNA (dsRNA), the genetic material for many RNA viruses, induces robust host immune responses via pattern recognition receptors, which include Toll-like receptor 3 (TLR3), …

2024年8月27日 · Mitochondria have the peculiarity of generating double-stranded RNA (dsRNA) molecules as a result of the normal process of bidirectional and overlapping transcription of its …

Historically, double-stranded RNA (dsRNA) has been considered as a byproduct of viral replication in mammalian cells for more than 30 years. This property of replicating viruses is …

2004年9月15日 · Double-stranded RNA (dsRNA) is an important regulator of gene expression in many eukaryotes. It triggers different types of gene silencing that are collectively referred to as …

1996年1月1日 · This chapter focuses on the structure and physicochemical properties of double stranded RNA (dsRNA); on the enzymes that degrade, modify, or otherwise modulate dsRNA …

Double-stranded RNA (dsRNA) sensor proteins and activation of innate immunity. Viral dsRNA (including 5′ phosphorylation) or dsRNA from mitochondria and repetitive elements in the …

2023年12月19日 · During the 1970s, scientists realized viral infection of mammalian cells generated viral double-stranded RNA (dsRNA) that inhibited protein synthesis 1, 2 and …

2023年2月2日 · Researchers have been harnessing the power of dsRNA for a long time, even before we knew about all the diverse in vitro production mechanisms. siRNA, also known as …