Regulation of eIF4E guides a unique translational program to …
2022年12月23日 · In this study, we characterized a dynamic progressive repression of eIF4E activity by hypophosphorylation of 4EBP1 throughout erythropoiesis. However, this fluctuation …
The RALF1–FERONIA Complex Phosphorylates eIF4E1 to
2020年5月4日 · We found that RALF1 promotes FERONIA-mediated phosphorylation of eIF4E1, a eukaryotic translation initiation factor that plays a crucial role in the control of mRNA …
Distinct recruitment of human eIF4E isoforms to processing bodies …
2016年8月30日 · Eukaryotic translation initiation factor 4E (eIF4E) plays a pivotal role in the control of cap-dependent translation initiation, modulates the fate of specific mRNAs, occurs in …
eIF4E1b is a non-canonical eIF4E protecting maternal dormant …
2023年12月14日 · Here we report that the germline-specific eIF4E paralog, eIF4E1b, is essential for zebrafish oogenesis. eIF4E1b localizes to P-bodies in zebrafish embryos and binds to …
Accumulation of Polyadenylated mRNA, Pab1p, eIF4E, and eIF4G …
Our results demonstrate that eIF4E, eIF4G1, eIF4G2, and Pab1p can all be detected to accumulate to some degree in P-bodies under glucose deprivation, and more strikingly in …
Deficiency of the eIF4E isoform nCBP limits the cell-to-cell
2017年1月6日 · Here, we show that another eIF4E family gene, nCBP, acts as a novel recessive resistance gene in Arabidopsis thaliana toward plant viruses in Alpha- and Betaflexiviridae.
Mammalian eIF4E2-GSK3β maintains basal phosphorylation of p53 …
2022年5月14日 · Here, we found that eIF4E2, a hypoxia-activated translation initiation factor, interacted with GSK3β to maintain phosphorylation of p53, thus resisting senescence under …
eIF4E1 Regulates Arabidopsis Embryo Development and Root …
2022年6月29日 · Yeast two-hybrid assays identified that eIF4E1 interacts with an RAC/ROP GTPase activator, RopGEF7, which has been previously reported to be involved in the …
MSCV eIF4E IRES GFP - Addgene
Plasmid MSCV eIF4E IRES GFP from Dr. Scott Lowe's lab contains the insert eIF4E and is published in Nature. 2004 Mar 18. 428(6980):332-7. This plasmid is available through Addgene.
Loss-of-Function Analysis Reveals Distinct Requirements of the ...
Our results show that eIF4E-1 function in early germ cells and the surrounding somatic cells is critical for spermatogenesis. Both eIF4E-1 and eIF4E-3 are required in spermatocytes for …