
Cloning and Characterization of Human eIF4E Genes
1998年2月20日 · Two human eukaryotic initiation factor 4E (eIF4E) genes were isolated and characterized from placental and chromosome 4-specific genomic libraries.
eIF4E-independent translation is largely eIF3d-dependent
2024年8月6日 · We study here how mRNAs are translated in an eIF4E1-independent manner by blocking eIF4E1 using a constitutively active version of eIF4E-binding protein (4E-BP). Via …
Therapeutic suppression of translation initiation factor eIF4E ...
2007年9月4日 · eIF4E expression is reduced in cultured human and murine cells. (A) eIF4E expression was assessed by quantitative RT-PCR. Representative data are shown for human …
eIF4E is a central node of an RNA regulon that governs cellular ...
2006年11月6日 · This study demonstrates that the eukaryotic translation initiation factor eIF4E is a critical node in an RNA regulon that impacts nearly every stage of cell cycle progression. …
PRSS23-eIF4E-c-Myc axis promotes gastric tumorigenesis and
2025年2月7日 · Our investigation revealed that PRSS23 interacts with eIF4E via its trypsin domain, while eIF4E binds to PRSS23 through the amino acid residue S209, as confirmed by …
真核起始因子4E - 维基百科,自由的百科全书
真核起始因子4E(英文:eukaryotic initiation factor 4E,简称“eIF4E”)是一种帽结合蛋白,可以特异性地识别mRNA的5'端的帽子结构,它在真核翻译的起始过程中发挥重要作用。
Identification and Characterization of an eIF4e DNA Aptamer That ...
Here, we demonstrate a method for the rapid selection of looped DNA aptamers against eIF4e by combining negative selection and purification in a single step, followed by characterization with …
Phosphorylation of eIF4E promotes EMT and metastasis via
2014年6月9日 · We demonstrate that phosphorylation of eIF4E promotes invasion in transformed MEFs, as well as transforming growth factor-beta (TGFβ)-induced EMT in normal epithelial …
Regulation of Eukaryotic Initiation Factor 4E (eIF4E) …
The m7G cap binding protein eukaryotic initiation factor 4E (eIF4E) is a rate-limiting determinant of protein synthesis. Elevated eIF4E levels, commonly associated with neoplasia, promote …
Eif4e - PCR Primer Pair - SYBR | PrimePCR | Bio-Rad
Real-time PCR primer assay designed for SYBR ® Green gene expression analysis. Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for …