Eukaryotic initiation factor 4F (eIF4F) is a heterotrimeric protein complex that binds the 5' cap of messenger RNAs (mRNAs) to promote eukaryotic translation initiation. The eIF4F complex is …

eIF4F（eukaryotic translation initiation factor 4F，真核起始因子4F）是一种在真核翻译起始中发挥重要功能的复合物。 eIF4F由 eIF4A 、 eIF4E 、 eIF4G 三个起始因子组成。

Eukaryotic translation initiation factor 4F (eIF4F) is a protein complex that mediates recruitment of ribosomes to mRNA. This event is the rate-limiting step for translation under most …

“翻译守门人”：eIF4F复合物的复杂协作. eIF4F，这个由三个亚基组成的分子机器通过协同合作，确保mRNA成功加载到核糖体，从而开启蛋白质的翻译 ...

2023年5月4日 · In this Perspective article, we discuss how eIF4F-sensitive mRNA translation controls the phenotypes of key non-transformed cells in the TME, with an emphasis on the …

2024年6月6日 · The eIF4F complex is required to activate mRNAs and recruit them to the small subunit. The core components of the complex—eIF4E, eIF4G, and eIF4A—each fulfill a …

2015年10月2日 · By physical analysis, eIF4F was a heterotrimeric complex of eIF4A, eIF4E, and eIF4G (1). The next studies were to attempt to identify the functions of the various proteins …

4 天之前 · Introduction. Eukaryotic translation initiation factor 4F (eIF4F) is required for the preinitiation complex (PIC) assembly at capped messenger RNA (mRNA) and the subsequent …

Formation of eukaryotic initiation factor 4F (eIF4F) is widely considered to be the rate-limiting step in cap-dependent translation initiation. Components of eIF4F are often up-regulated in various …

1 天前 · 导读. eif4f复合物 （eif4e、eif4g、eif4a）在帽依赖性翻译起始中至关重要。 eif4e识别5′帽结构，eif4a作为rna解旋酶，eif4g作为支架蛋白，与eif3结合促进48s pic组装。eif4a受eif4b增 …