Eukaryotic translation initiation factor 5A-1 is a protein that in humans is encoded by the EIF5A gene. [5] It is the only known protein to contain the unusual amino acid hypusine [N ε-(4-amino …

2024年12月24日 · EIF5A (Eukaryotic Translation Initiation Factor 5A) is a Protein Coding gene. Diseases associated with EIF5A include Faundes-Banka Syndrome and Non-Specific …

2021年12月24日 · Since the demonstration of its involvement in cell proliferation, the eukaryotic initiation factor 5A (eIF5A) has been studied principally in relation to the development and …

2024年12月1日 · Among these factors, eukaryotic translation initiation factor 5 A (eIF5A) emerges as a crucial translation factor with high evolutionary conservation. eIF5A is unique as it is the …

2017年4月20日 · Using a combination of ribosome profiling and in vitro biochemistry, we report a much broader role for eIF5A in elongation and uncover a critical function for eIF5A in …

真核翻译起始因子5A（eukaryotic translation initiation factor 5A, eIF5A）是维持细胞活性必不可少的翻译因子，在进化上高度保守。 eIF5A是真核细胞中唯一含有羟腐胺赖氨酸（hypusine）的 …

2020年12月28日 · 最新的研究数据表明，hypusinated化的EIF5A能够调节如自噬、衰老、多胺稳态、能量代谢等一系列关键的细胞进程，并在癌症中起作用。 然而，目前在临床前癌症模型 …

真核翻译起始因子5A（eukaryotic translation initiation factor 5A, eIF5A）是维持细胞活性必不可少的翻译因子,在进化上高度保守。 eIF5A是真核细胞中唯一含有羟腐胺赖氨酸（hypusine）的 …

Enables U6 snRNA binding activity and protein N-terminus binding activity. Involved in several processes, including cellular response to virus; positive regulation of intrinsic apoptotic …

2022年12月17日 · Here we show that the function of the elongation factor, eIF5a, is regulated dynamically in naïve CD8 + T cells upon activation by post-translational modification, …