Welcome to the home of Palliative Care Fast Facts and Concepts—originally published by EPERC since 2000. Fast Facts are edited by Sean Marks, MD; Associate Professor of …

Background Patients referred to palliative care services often have between 3 and 7 distressing symptoms and may require multiple medications for effective symptom reduction (1). Due to its …

This Fast Fact will address the natural history and illness trajectory of Parkinson’s Disease (PD). See Fast Fact #362 for information on palliation strategies of non-motor symptoms associated …

Background This Fast Fact reviews prognostication data in Heart Failure (HF). Although the Framingham Heart Study (1990-1999) showed a 5-year mortality rate of 50% for newly …

Background for FF #20 A common question from trainees is “How fast, and by how much, can opioids be safely dose escalated in terminally ill patients?” Consider the analogy of furosemide …

Systemic opioids have been predominantly utilized for wound-related pain, however, for many patients, dose-limiting side effects can hinder their effectiveness. This Fast Fact will discuss …

Background for Fast Fact #142 Opioid-induced hyperalgesia is a clinical phenomenon, characterized by increasing in pain in patients who are receiving increasing doses of opioids. …

This Fast Facts discusses pharmacologic management strategies for patients with ALS; see Fast Fact #300 for non-pharmacologic management strategies and Fast Fact #299 for management …

Background This Fast Fact addresses analgesic management for patients taking buprenorphine for opioid use disorder (OUD). Buprenorphine is a mixed opioid agonist/antagonist, available in …

Background: This Fast Fact reviews available published evidence and expert opinion regarding prognostication for amyotrophic lateral sclerosis (ALS), an incurable, progressive …