The hnRNP family: insights into their role in health and disease
2016年5月23日 · Heterogeneous nuclear ribonucleoproteins (hnRNPs) represent a large family of RNA-binding proteins (RBPs) that contribute to multiple aspects of nucleic acid metabolism …
Regulation of HNRNP family by post-translational modifications in ...
2024年10月4日 · The HNRNP Q, also known as GRY-RBP, NSAP1, or SYNCRIP, has an acidic amino acid in the N-terminal region, which has three consecutive RRMs, and one of them …
The Roles of hnRNP Family in the Brain and Brain-Related Disorders
2023年11月24日 · Heterogeneous nuclear ribonucleoproteins (hnRNPs) are a family of RNA-binding proteins that bind to the primary transcripts of protein-coding genes. hnRNPs play a …
hnRNP Q regulates translation of p53 in normal and stress
2012年8月31日 · Under both normal and stress circumstances, hnRNP Q binds to the 5′UTR of mouse p53 mRNA and regulates translation efficiency, without affecting mRNA levels. In …
异质核糖核蛋白 Q（HNRPQ）｜ELISA指标_hnRNP_细胞核_功能
2025年3月11日 · 异质核糖核蛋白 Q（heterogeneous ribonucleoprotein Q，hnRNP Q）是一种在细胞内发挥多种重要作用的蛋白质，以下是关于它的详细介绍： 基本结构与特点. 结构组 …
The RNA binding protein hnRNP Q modulates the utilization of
Using affinity chromatography, we identified several SMN RNA-associating proteins in mouse testis and human HeLa cells, including hnRNP Q. The major hnRNP Q isoform, Q1, directly …
The hnRNP family: insights into their role in health and disease
Heterogeneous nuclear ribonucleoproteins (hnRNPs) represent a large family of RNA-binding proteins (RBPs) that contribute to multiple aspects of nucleic acid metabolism including …
hnRNP Q Regulates Internal Ribosome Entry Site-Mediated
2019年2月4日 · Here, we unambiguously demonstrate that the fmr1 gene, which encodes FMRP, exploits both IRES-mediated translation and canonical cap-dependent translation. …
Systematic Analysis of Gene Expression Profiles Controlled by hnRNP Q …
Nonetheless, our study sheds light on the distinctive functions of hnRNP Q and hnRNP R in human neuronal cells and, in general, provides insights on the involvement of the hnRNP …
The RNA-binding protein hnRNP Q represses translation of the clock …
2019年5月10日 · In this study, we determine that an RNA-binding protein, hnRNP Q, has a critical role in translational control of Bmal1 mRNA. We also show that hnRNP Q binds to a specific …