The broad-spectrum antiviral functions of IFIT and IFITM proteins
2012年12月14日 · IFN-induced protein with tetratricopeptide repeats (IFIT) proteins — which are induced after type I interferon (IFN)- or IFN-regulatory factor 3 (IRF3)-dependent signalling — …
IFIT2 Gene - GeneCards | IFIT2 Protein | IFIT2 Antibody
2024年12月25日 · IFIT2 (Interferon Induced Protein With Tetratricopeptide Repeats 2) is a Protein Coding gene. Diseases associated with IFIT2 include Microphthalmia With Limb Anomalies …
How Different Pathologies Are Affected by IFIT Expression
SARS-CoV-2, in particular, has emerged as a novel cause of viral sepsis due to its wide arsenal of viral proteins that diminish the translation of IFIT proteins. By understanding the role of IFIT …
(PDF) IRF7 and IFIT2 in mediating different hemorrhage
2023年4月1日 · Higher IRF7 levels and lower IFIT2 levels in LUAD tumors were associated with higher MVD in LUAD tissues, which may be responsible for the different hemorrhage …
Interferon Induced IFIT Family Genes in Host Antiviral Defense
An intriguing, newly found antiviral mechanism of IFIT family genes is the ability of IFIT family proteins to directly bind viral RNA. Viral RNA that carries 5'PPP-RNA is recognized by IFIT1, …
Lineage-Specific Expansion of IFIT Gene Family: An Insight into ...
2013年6月20日 · Thus, the activation of zebrafish IFIT gene promoters by IRF3 or IRF7 was investigated. As shown in Figure 7C, overexpression of zebrafish IRF3 or IRF7 in EPC cells …
干扰素诱导蛋白与四肽重复 2（IFIT2）基因 | MCE
干扰素诱导蛋白与四肽重复 2： 启用 rna 结合活性。参与蛋白结合活性的负调控；凋亡过程的正调控；和对病毒的反应。位于内质网。 [由基因组资源联盟提供，2022 年 4 月]
干扰素诱导的四肽重复序列(IFIT)基因家族蛋白抗病毒作用机制研究 …
2021年9月10日 · RLR与MAVS之间的CARD-CARD相互作用可以激活干扰素激酶，进一步磷酸化激活相应的IRF3或IRF7，以及细胞核因子κB (NF-κB)，诱导干扰素-α/β (IFN-α/β)表达 [11]。 …
Roles of interferon induced protein with tetratricopeptide repeats ...
2023年11月1日 · Interferon-induced tetrapeptide repeat (IFIT) family proteins are an important component of the antiviral immune response. There are four known members of the human …
Emerging Functions of Human IFIT Proteins in Cancer
2019年12月19日 · Interferon-induced protein with tetratricopeptide repeats (IFIT) genes are prominent interferon-stimulated genes (ISGs). The human IFIT gene family consists of four …