Overview of the many logP and other physical property calculators available commercially and on-line. XLOGP3, a simple LogP estimator used by PubChem (release 2021.05.07)

2024年1月6日 · LogP measures the logarithm of ration between the concentration of a compound in a non-polar solvent and in water. It is common practice to measure this using octanol …

LogP is the log of the partition coefficient of a solute between octanol and water, at near infinite dilution. LogP is widely used in drug discovery and development as an indicator of potential …

2024年10月29日 · LogP and logD are important values to consider during drug design as both give insight to the lipophilicity and hydrophilicity of compounds.

2022年12月14日 · Since most solutes will heavily favor one solvent over the other, the concentration in each layer will differ by several magnitudes. Therefore, we often use log P …

LogP, or octanol-water partition coefficient, is a measure of how hydrophilic or hydrophobic a molecule is. It indicates how readily an analyte will partition between an aqueous and organic …

How Can I Obtain LogP Values? The partition coefficient of a compound can be experimentally measured using a variety of widely accepted methods. The two most common methods are …

LogP is equivalent to logD for non-ionisable compounds and represents the partition of the neutral form for ionizable compounds (and, hence, is a virtual, unmeasurable, property).

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2022年9月3日 · LogP gives you an indication of how well the molecule will partition into the organic elution solvent. The higher the logP, the more likely the compound will partition from …