Our mRNA pipeline shows the progress we’re making on clinical programs currently in development to create mRNA medicines for a wide range of diseases and conditions.

2024年3月27日 · Moderna's respiratory pipeline includes Phase 3 trials for investigational vaccines including a next-generation COVID-19 vaccine, an RSV vaccine, a flu vaccine, and a flu and COVID-19 combination vaccine. The pipeline includes three additional flu vaccine candidates with expanded antigen coverage as well as combination vaccine programs. COVID-19

2025年3月6日 · In a wholly owned program, Arcturus is developing a messenger RNA (mRNA) medicine to treat ornithine transcarbamylase deficiency, a life-threatening genetic disease that affects over 10,000 people worldwide. OTC is a key urea cycle enzyme in liver cells that helps eliminate ammonia from the body.

Whether mRNA, cell therapies, antibodies or small molecule immunomodulators | learn all about our technical approaches for oncology and infectious diseases.

2023年1月9日 · Moderna and Merck announced mRNA-4157/V940, in combination with KEYTRUDA, demonstrated a 44% reduction in the risk of disease recurrence or death in melanoma patients. Phase 3 study in melanoma patients to start in 2023, with rapid expansion to additional tumor types.

2025年1月13日 · Next-generation COVID-19 vaccine: Moderna shared positive Phase 3 vaccine efficacy and immunogenicity data for its next-generation COVID-19 vaccine (mRNA-1283) at its 2024 R&D Day event. The Company has filed for regulatory approval of mRNA-1283 using a priority review voucher.

AstraZeneca’s deep pipeline of medicines focusing on their key therapeutic areas.

2023年6月16日 · Messenger RNA (mRNA) vaccines work differently compared to other vaccines. For example, other vaccines may contain weakened or dead germs (or part of the germ). This trains your immune system to quickly recognize and fight the germ if you’re exposed to it in the future. But mRNA vaccines don’t contain germs at all.

Our infrastructure enables rapid supply of thousands of pre-clinical mRNAs for in vitro and in vivo research to accelerate programs from idea to development candidate designation. Our Research Engine combines proprietary digital drug design tools and a highly automated production facility to enable Moderna to advance mRNA vaccines and therapeutics.

mRNA Analysis Pipeline Introduction. The GDC mRNA quantification analysis pipeline measures gene level expression with STAR as raw read counts. Subsequently the counts are augmented with several transformations including Fragments per Kilobase of transcript per Million mapped reads (FPKM), upper quartile normalized FPKM (FPKM-UQ), and ...