The miR-375 microRNA (miRNA) is a short RNA molecule located on human chromosome 2 in between the CRYBA2 and CCDC108 genes. [1] miRNAs are small (18–25 nucleotides), non …

2024年12月25日 · MIR375 (MicroRNA 375) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR375 include Lung Cancer Susceptibility 3 and Diabetes …

2021年9月30日 · MiR-375 is a conserved noncoding RNA that is known to be involved in tumor cell proliferation, migration, and drug resistance. Previous studies have shown that miR-375 …

2021年3月18日 · MiR-375 is of vital importance in diabetes through the regulation of expression of relative genes concerning islets formation, pancreatic development and secretion of β-cells. …

2025年2月8日 · An integrative bioinformatics analysis identified miR-375 as a candidate key regulator of malignant breast cancer. Liu J, et al. J Appl Genet, 2019 Nov. PMID 31372832; …

2024年4月2日 · Mechanistically, we show that miR-375 predominantly targets genes possessing oncogenic roles (e.g., proliferation, DNA repair, and metastasis), and thus release targets with …

2021年6月15日 · MiR-375, a primitively described beta cell-specific miRNA, is confirmed to function as multi-functional regulator in diverse typical cellular pathways according to the …

胰岛中最丰富的miRNA之一是miR-375。 这篇综述集中在miR-375在β细胞功能中的作用，包括对胰岛素分泌的发展和分化，增殖和调节的影响。 它还讨论了miR-375表达的调节，miR-375作 …

2014年1月1日 · MiR-375 is an important small non-coding RNA that is specifically expressed in islet cells of the pancreas. miR-375 is required for normal pancreatic genesis and influences …

2018年1月24日 · Ectopic expression of miR-375 inhibited tumor growth in vitro and in vivo. Three components of Hippo pathway, YAP1, TEAD4 and CTGF, were revealed to be direct targets of …