Haplogroup J is a human mitochondrial DNA (mtDNA) haplogroup. The clade derives from the haplogroup JT, which also gave rise to haplogroup T. Within the field of medical genetics, certain polymorphisms specific to haplogroup J have been associated …

J1c is by far the most common form of mtDNA J in Europe today, making up over three quarters of all J lineages. One question that follows is: did J1c and J2b1a lineages actually come from the Near East during the Neolithic, or whether they were already in …

Variability of human mitochondrial DNA has provided valuable data about the genetic past of human maternal lineages. Analyses of the frequency, variation and distribution of mitochondrial DNA haplotypes have been used to evaluate current models concerning the process of colonization of the World.

Haplogroup J, a mitochondrial DNA lineage, originated approximately 45,000 years ago in West Asia, splitting into subclades J1 and J2 over the following millennia.

Find out which of the J branches and 119 countries that you belong to with the most comprehensive mtDNA test! Every new mtFull Sequence test result helps improve the tree structure and age estimates. A popular genealogy strategy is to expand your part of the tree by encouraging distant relatives to test.

Mitochondrial DNA haplogroup J is the third most frequent haplogroup in modern‐day Scandinavia, although it did not originate there. To infer the genetic history of haplogroup J in Scandinavia, we examined worldwide mitogenome sequences using a maximum‐likelihood phylogenetic approach.

2025年3月10日 · a, mtDNA heteroplasmy-shifting tools, which use site-specific nucleases to degrade mutant mtDNA, allowing the remaining wild-type mtDNA to repopulate and thereby shifting the balance towards a ...

Our results demonstrate significant structural and functional differences between mtDNA haplogroups H vs. J-containing cybrid cells. Our study suggests that the J mtDNA haplogroup can alter the transcriptome to increase cellular susceptibility to stress and retinal degenerations.

Haplogroup J is a human mitochondrial DNA (mtDNA) haplogroup. The clade derives from the haplogroup JT, which also gave rise to haplogroup T. Within the field of medical genetics, certain polymorphisms specific to haplogroup J have been associated …

In summary, this study shows that carriers of the mtDNA haplogroup J show a significantly higher telomere length of PBL than non-J carriers, as well as a decreased NO production and lower iNOS mRNA levels in cultured chondrocytes, indicating that this haplogroup, which is clearly biochemically different from those of other population-specific ...