2020年7月20日 · Oxidized LDL, or oxLDL, is a type of low-density lipoprotein (known as LDL cholesterol) that has become damaged by a chemical reaction with harmful molecules known …

2022年9月15日 · Oxidized cholesterol is made in the body when low-density lipoprotein (LDL), sometimes called “bad” cholesterol, goes through a chemical reaction. Oxidized cholesterol is …

Measurement of oxidized LDL (oxLDL) has been incorporated into clinical practice in the diagnosis and treatment of lipid disorders (such as diabetes mellitus), atherosclerosis, and various liver and renal diseases, especially as it pertains to the evaluation of oxidative stress.

OxLDL can have both pro-inflammatory and anti-inflammatory properties concerning the stage of oxLDL exposure and the degree of oxidation. One of the possible mechanisms underlying the atheroprotective effect of oxLDL may be an oxLDL-triggered miR-29a up-regulation.

One potential marker of MetS risk is oxidized LDL (oxLDL), which is formed when oxidative stress leads to modification of the apoB subunit on LDL cholesterol (LDL). Conversion of LDL to oxLDL appears to be an important event that helps initiate and accelerate the development of early atherosclerotic lesions, or fatty streaks.

One biomarker of MetS risk is oxidized LDL (oxLDL), which is formed when oxidative stress leads to modification of the apoB subunit on LDL cholesterol (LDL). Conversion of LDL to oxLDL is an important event that initiates foam cell formation during the development of early atherosclerotic lesions, or fatty streaks.

OxLDL measures protein damage due to the oxidative modification of the ApoB subunit on LDL cholesterol. The oxidation of LDL cholesterol is one of the first steps in the development of atherosclerosis. Briefly, LDL-C enters the artery wall where it becomes oxidized.

Oxidized LDL (OxLDL) What is OxLDL? Think of OxLDL as damaged LDL. LDL is often called the “bad” cholesterol, because high levels of LDL can lead to heart disease and heart attacks. Damaged or oxidized LDL is even more likely to invade the walls of your blood vessels and increases your risk of heart disease. Why check my OxLDL level?

Oxidized low-density lipoprotein (Ox-LDL) has been studied for over 25 years. Numerous pro- and anti-atherogenic properties have been attributed to Ox-LDL. Yet, Ox-LDL has neither been defined nor characterized, as its components and composition change depending on its source, method of preparation, storage, and use.

Oxidized LDL (oxLDL) is known to be associated with excessive inflammation and abnormal lipoprotein metabolism. Chronic inflammatory diseases confer an elevated risk of premature atherosclerosis and adverse cardiovascular events.