The pigmented layer of retina or retinal pigment epithelium (RPE) is the pigmented cell layer just outside the neurosensory retina that nourishes retinal visual cells, and is firmly attached to the underlying choroid and overlying retinal visual cells.

Retinal pigment epithelium (RPE) is formed from a single layer of regular polygonal cells arranged at the outermost layer of the retina. The outer side of the RPE is connected to Bruch’s membrane and the choroid, while the inner side is connected to the outer segment of photoreceptor cells.

RPE cells carry out many functions including the conversion and storage of retinoid, the phagocytosis of shed PR outer segment membrane, the absorption of scattered light, ion and fluid transport and RPE-PR apposition.

The retinal pigment epithelium (RPE), a monolayer of post-mitotic polarized epithelial cells, strategically situated between the photoreceptors and the choroid, is the primary caretaker of photoreceptor health and function.

2024年11月1日 · The retinal pigment epithelium (RPE) between retinal photoreceptors and choroidal capillaries is a single layer of cells that are of critical importance to the eye. RPE cells are derived from the anterior neural plate of neuroectodermal origin.

The retinal pigment epithelium (RPE) forms an important cellular monolayer, which contributes to the normal physiology of the eye. Damage to the RPE leads to the development of degenerative diseases, such as age-related macular degeneration (AMD). ...

2011年1月26日 · Functional interaction of both the pigmented cell and the photoreceptor cells is essential for visual function (2-5). Already beginning with the embryonic development the functional differentiation of the photoreceptor layer and the retinal pigment epithelium (RPE) depend on each other (6, 7).

Photoreceptor cells are highly specialised cells that absorb light and, through a cascade of chemical signals, convert it into electrical information needed to visualise an image. Beneath the photoreceptors is the retinal pigment epithelium (RPE).

2020年9月1日 · From a developmental perspective, the RPE is a neuroepithelium, derived from the outer layer of the optic cup. Functionally, the RPE acts as a secretory epithelium, a regulatory barrier, a professional phagocyte, and an antigen-presenting cell.

The retinal pigment epithelium (RPE) is a single monolayer of cells that resides between the light-sensitive photoreceptors and the fenestrated choriocapillaris. It performs specific functions in support of the photoreceptor cells, including the reisomerization of visual chromophore, and phagocytosis of photoreceptor outer segment (POS ...