Integration of tDCS with MR imaging techniques provides a tool to directly perturb neuronal function while monitoring brain state. Therefore, it enables researchers to study not only how stimulation modulates targeted brain regions, but also how tDCS modulates activity across the brain in the context of anatomical and functional connectivity.

Transcranial direct current stimulation (tDCS) is a popular brain stimulation method that is used to modulate cortical excitability, producing facilitatory or inhibitory effects upon a variety of behaviors.

2016年10月4日 · Transcranial direct current stimulation (tDCS) is an emerging non-invasive neuromodulation technique that applies mA currents at the scalp to modulate cortical excitability. Here, we...

2024年11月20日 · Transcranial direct current stimulation (tDCS) has emerged as a valuable neuromodulation technique. Many clinical conditions are associated with brain damage, and in severe cases, structural changes such as skull defects are common. These clinical characteristics result in distinct electrical flow p …

In this systematic review, we explore methodological parameter space of tDCS integration with fMRI spanning: (a) fMRI timing relative to tDCS (pre, post, concurrent); (b) study design (parallel, crossover); (c) control condition (sham, active control); (d) number of tDCS sessions; (e) number of follow up scans; (f) stimulation dose and ...

This section will discuss how tDCS has been integrated with fMRI, both in terms of Blood Oxygen Level Dependent (BOLD) fMRI (Baudewig et al. 2001) and Arterial Spin Labeling (ASL; Zheng et al. 2011; Stagg et al. 2013); as well as proton and non-proton MR Spectroscopy (MRS; Rango et al. 2008; Stagg et al. 2009; Binkofski et al. 2011; Clark et al ...

2025年3月6日 · 本研究旨在直接从T1加权 磁共振成像 （MRI）生成tDCS电场图，以提供高效的个性化tDCS剂量估计方法。 方法： 采用深度学习方法，并结合特殊损失正则化策略，以提高模型在个体扫描和电极布置上的泛化能力和校准能力。

2021年9月21日 · Magnetic resonance imaging approaches have the potential to study the modulation of brain activity by tDCS, and here we review the functional MRI and MR spectroscopy studies involving tDCS. We review the basis of the most commonly used approaches for both fMRI acquired at rest and during a task performance.

2022年12月5日 · This study aims to determine the effectiveness of personalized tDCS using brain MRI-based electrical field simulation and optimization, to enhance motor recovery of the upper limbs in the patients. This trial is a double-blind, randomized controlled trial in the subacute to chronic rehabilitation phase.

However, the hemodynamic and neuronal metabolic responses to tDCS, particularly in real-time with tDCS-MRI, remain underexplored. This study investigates cerebral metabolic rate of oxygen (CMRO2) and cerebral blood flow (CBF) responses to tDCS in MS, examining both concurrent and post-tDCS effects.