Transfer-messenger RNA (abbreviated tmRNA, also known as 10Sa RNA and by its genetic name SsrA) is a bacterial RNA molecule with dual tRNA -like and messenger RNA -like properties. The tmRNA forms a ribonucleoprotein complex (tmRNP) together with Small Protein B (SmpB), Elongation Factor Tu (EF-Tu), and ribosomal protein S1.

tmRNA, from wikipedia 这种RNA主要帮助保证细菌蛋白质翻译的保真性，通过'ribosome rescue' 来回收停滞的核糖体。 简单来讲，在基因表达的时候，核糖体有时候会因为各种各样的原因停在mRNA上，比如说缺失终止密码子等等。

2020年8月18日 · 转运-信使RNA（Transfer-messenger RNA），是一种细菌的RNA分子，是tRNA和信使RNA类似物。 tmRNA的用途十分广泛，它可用于回收停滞的核糖体，并有利于异常的信使RNA的降解。

转运-信使RNA（Transfer-messenger RNA），是一种细菌的RNA分子，是tRNA和信使RNA类似物。 tmRNA的用途十分广泛，它可用于回收停滞的核糖体，并有利于异常的信使RNA的降解。

The bacterial tmRNA quality control system monitors protein synthesis and recycles stalled translation complexes in a process termed “ribosome rescue”. During rescue, tmRNA acts first as a transfer RNA to bind stalled ribosomes, then as a messenger ...

The transfer-messenger RNA (tmRNA) and its partner protein SmpB act together in resolving problems arising when translating bacterial ribosomes reach the end of mRNA with no stop codon. Their genes have been found in nearly all bacterial genomes and ...

摘要： tmRNA是一类具有类似tRNA分子和mRNA分子双重功能的小分子RNA，它在一种特殊的翻译模式——反式翻译模式过程中发挥重要作用。 最近又发现它与基因的表达调控及细胞周期的调控等生命过程密切相关。

Transfer-messenger RNA (tmRNA) is a bifunctional RNA that has properties of a tRNA and an mRNA. tmRNA uses these two functions to release ribosomes stalled during translation and target the nascent polypeptides for degradation.

2024年5月30日 · What is Transfer-messenger RNA (tmRNA)? Transfer-messenger RNA (tmRNA), also known as 10Sa or SsrA RNA, is exceptional among bifunctional RNAs in that it possesses both tRNA and mRNA characteristics. tmRNA employs these two activities to liberate translationally stalled ribosomes and to target nascent polypeptides for destruction.

The bacterial tmRNA quality control system monitors protein synthesis and recycles stalled translation complexes in a process termed "ribosome rescue." During rescue, tmRNA acts first as a transfer RNA to bind stalled ribosomes, then as a messenger RNA to add the ssrA peptide tag to the C-terminus o …