2021年2月10日 · The Taurus armoured recovery vehicle (ARV) is designed to recover and tow vehicles bogged down or disabled by enemy action or mechanical failure. It is also capable of carrying out bulldozing operations, changing components such as turrets on other vehicles, and fuelling vehicles.

2021年2月10日 · The Leopard 2 Family of Vehicles (FOV) are the main battle tanks (MBT) of the Canadian Armed Forces, as well as several NATO countries. This FOV includes the Armoured Engineer Vehicles (AEV) and Armoured Recovery Vehicles (ARV), and are capable of supporting a wide range of operations.

It includes the land equipment in use by the Canadian Army and Primary Reserve, the Canadian Special Operations Forces Command, the Canadian Joint Operations Command, the Royal Canadian Navy, and the Royal Canadian Air Force.

It was to replace the GDLS-Canada 6x6 family of Armoured Vehicle General Purpose (AVGP) comprising the Grizzly, Cougar and Husky from the late 1970s. It joins a fleet of relatively similar vehicles, the Bison APC (1988) and the LAV-III IFV (1999)) based on the 8x8 Mowag Piranha II and IIIH versions respectively.

2017年4月24日 · Application: This DAOD is an order that applies to officers and non-commissioned members of the Canadian Armed Forces in the Regular Force (Reg F) and the Primary Reserve (P Res) (CAF members). Supersession:

The AVGP (Armoured Vehicle General Purpose) is a series of three armoured fighting vehicles ordered by the Canadian military in 1977. The three vehicles are the Cougar, Grizzly and Husky. These vehicles were based on the six-wheeled version of the Swiss MOWAG Piranha I.

肿瘤组织中大量的 肿瘤相关成纤维细胞（cancer associated fibroblasts, CAFs） 为肿瘤的发展构建了良好的环境（占基质细胞50%以上）。 CAFs在癌症中扮演重要作用：CAFs不仅可通过分泌多种细胞因子或代谢产物抑制免疫细胞的功能，促进肿瘤发展、侵袭、转移；CAFs 还具有塑造肿瘤外基质、形成药物或治疗性免疫细胞渗透屏障的阻止药物与免疫细胞向肿瘤组织的深层渗透，从而降低肿瘤治疗效果。 因此，通过调控 CAFs 或克服其屏障作用抑制肿瘤是肿瘤治疗的新手段 …

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肿瘤相关成纤维细胞 (CAF)是 肿瘤微环境 (TME)的一种异质性细胞成分，具有高度可塑性。 最近的研究揭示了不同癌症中的CAF亚型，并确定了关键的CAF亚型，如 肌成纤维细胞CAF 、 炎性CAF 和 抗原提呈CAF，前两种CAF几乎存在于所有肿瘤中。 重要的是，这三个CAF亚型参与并调节了TAI。 CAF的显著可塑性使它们能够随着环境的变化而在表型和功能上发生变化。 今天给大家介绍一篇关于CAF的综述，在这篇综述中，作者描述了CAF如何促进肿瘤炎症和抑制获得性免 …

2024年1月11日 · 研究列出了黑色素瘤MES细胞和CAF之间差异表达最多的50个基因，称之为最小谱系基因（MLG），用来定义黑色素瘤特异性MES基因特征。 MLG提供了一种独特的工具来明确区分黑色素瘤MES细胞和CAF。 由于MLG在MES细胞中的表达较低，研究人员开发了一种原位绘制MES单元的方法（RNAscope，与CODEX 兼容），采用该方法证实高比例的MES细胞的存在，这些数据提供了在scRNA-seq数据集和组织切片中明确识别黑色素瘤MES细胞的方法，并 …