OAS1 Gene - GeneCards | OAS1 Protein | OAS1 Antibody
2024年12月25日 · OAS1 (2'-5'-Oligoadenylate Synthetase 1) is a Protein Coding gene. Diseases associated with OAS1 include Immunodeficiency 100 With Pulmonary Alveolar Proteinosis …
Origin and development of oligoadenylate synthetase immune …
2018年12月27日 · We performed comprehensive phylogenetic and functional analyses of OAS genes from evolutionarily lower to higher Metazoa to demonstrate how the OAS repertoires …
OAS1, OAS2 and OAS3 restrict intracellular - ScienceDirect
2019年3月1日 · We show for the first time that OAS1, 2 and 3 restrict intracellular pathogenic mycobacterial replication and enhance pro-inflammatory cytokine secretion. Recent evidence …
Origin and development of oligoadenylate synthetase immune system
2018年12月27日 · Upon double-stranded RNA (dsRNA) binding, avian and mammalian OASs generate the second messenger 2'-5'-linked oligoadenylate (2-5A), which activates …
4938 - Gene ResultOAS1 2'-5'-oligoadenylate synthetase 1
This interferon-induced gene encodes a protein that synthesizes 2',5'-oligoadenylates (2-5As). This protein plays a key role in innate cellular antiviral response, and has been implicated in …
Enzymatically active 2',5'-oligoadenylate synthetases are widely ...
2',5'-Oligoadenylate synthetases (OASs) belong to the nucleotidyl transferase family together with poly(A) polymerases, CCA-adding enzymes and the recently discovered cyclic-GMP-AMP …
Gene structure of the murine 2′-5′-oligoadenylate synthetase family
The 2′-5′-oligoadenylate synthetases (OASs) are members of a family of interferon-induced proteins playing an important role in the antiviral effect of interferons as well as being involved …
Expression of the OAS Gene Family Is Highly Modulated in …
2018年9月17日 · OASs gene expression could be induced by infiltrating monocytes, activation by dsRNA viruses, or by necrotic/apoptotic events in muscle myositis. Moreover, the activation of …
Adaptive Evolution of the OAS Gene Family Provides New
2023年1月6日 · The oligoadenylate synthesis (OAS) gene family, which is an important component of the immune system, provides an essential response to the antiviral activities of …
Molecular characterization of the 2′,5′-oligoadenylate synthetase ...
2019年2月1日 · The IFN-induced 2′,5′-oligoadenylate synthetases (OASs) have been identified as a member of the ISGs family characterized by the ability to synthesize 2′,5′-oligoadenylate (2 …
- 某些结果已被删除