2022年12月8日 · Our results indicate that PNPase controls cellular metabolism by negatively regulating the crp operon via targeting the 5′-untranslated region of the crp transcript. This study reveals a persister mechanism and provides novel targets for the development of drugs against persisters for more effective treatment.

2018年4月30日 · Here, using Escherichia coli as a model, we identified polynucleotide phosphorylase (PNPase) as a key regulator in persister formation. We successfully constructed pnp knockout mutant strain and its complemented strain, and exposed the pnp knockout mutant and complemented strain to antibiotics and stress conditions.

Our results indicate that PNPase controls cellular metabolism by negatively regulating the crp operon at the post-transcriptional level by targeting the 5’- Untranslated Region (UTR) of the crp transcript.

C-reactive protein (CRP) is an acute inflammatory protein that increases up to 1,000-fold at sites of infection or inflammation. CRP is produced as a homopentameric protein, termed native CRP (nCRP), which can irreversibly dissociate at sites of ...

Our results indicate that PNPase controls cellular metabolism by negatively regulating the crp operon via targeting the 5-untranslated region of the crp transcript. This study reveals a persister mechanism. and provides novel targets for the development of drugs against persisters for more effec-tive treatment. sistent infections.

2022年12月8日 · Our results indicate that PNPase controls cellular metabolism by negatively regulating the crp operon via targeting the 5'-untranslated region of the crp transcript. This study reveals a...

2018年4月30日 · Our results indicate that PNPase controls cellular metabolism by negatively regulating the crp operon at the post-transcriptional level by targeting the 5- Untranslated Region (UTR) of the crp...

Lot of 35 pieces of genuine CRP military spec. Jan2n2907a PNP silicon transistors in the TO-18 metal package. These are the PNP compliment to the popular 2n2222A.

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Description "Robbe Modellsport LIMIT PRO PNP FULL GRP/CRP WITH MOTOR AND SERVOS" The "LIMIT Pro" is a classic hotliner in modern CFK/GFK shell construction with first-class all-round flight characteristics and impressive design. With the drive of the PNP version, breathtaking climbing flights are achievable.