Dennis Lynn Rader (born March 9, 1945), also known as BTK (an abbreviation he gave himself for " bind, torture, kill "), is an American serial killer who murdered at least 10 people in Wichita and Park City, Kansas, between 1974 and 1991. Although he occasionally killed or attempted to kill men and children, Rader typically targeted women.

2025年1月21日 · Two decades after the arrest of Dennis Rader, the infamous “BTK Killer” continues to intrigue true-crime fanatics. The 79-year-old and his crimes are the subject of the iHeartRadio podcast...

2018年8月31日 · From 1974 to 1991, serial killer Dennis Rader murdered 10 people under the moniker BTK Killer, standing for "Bind, Torture, Kill." Around his hometown of Wichita, Kansas, Rader was known as a family man and church leader, and no one suspected he was the man sending taunting letters to police and media detailing his brutal, twisted crimes.

La BTK est un établissement de crédit qui exerce en sa qualité de banque et à titre de profession les opérations énumérées à l'article 2 de la loi n°2001-65 du 10 juillet 2001 relative aux établissements de crédit.

2021年10月18日 · The perfect BTK Animated GIF for your conversation. Discover and Share the best GIFs on Tenor.

2024年2月22日 · Bruton酪氨酸激酶（BTK）是一种非受体激酶，在许多B细胞恶性肿瘤中扮演关键的致癌信号传导作用，对白血病细胞的增殖和存活至关重要。 BTK最初在 X连锁遗传无球蛋白血病 （XLA）中被发现缺陷，对B细胞的发育和成熟B细胞的功能均至关重要。 在被发现后不久，BTK被放置在B细胞抗原受体（BCR）下游的信号传导途径中。 最近，针对该激酶的小分子抑制剂已经在动物模型中展现出出色的抗肿瘤活性，并随后在临床研究中得到证实。 特别是口服的不可 …

Thank you guys for watching the video. I hope you all enjoy the video. Please like the video, comment me the best part share this video to your friends and s...

布鲁顿酪氨酸激酶（Bruton’s tyrosine kinase，BTK）是胞浆内非受体型酪氨酸激酶TEC家族中的一员，在B细胞生长发育、增殖分化过程中起着重要作用，同时也是B细胞恶性肿瘤的治疗靶点。

BTK是一种连接BCR信号、Toll样受体（TLR）信号和趋化因子受体信号的关键分子（图2）。 在抗原依赖性BCR信号中，BTK可被PI3K或SYK激活。 PI3K产生一种激活下游通路的必需信使PIP3，其常与BTK的PH域结合，使SYK和LYN通过Y551位点的完全转磷酸化激活BTK； 在趋化因子受体信号转导中，在骨髓和生发中心高度表达的CXCL12，通过BTK与CXCR4连接的异源三聚体G蛋白亚基直接相互作用，与CXCR4结合，诱导BTK活化； 在抗原非依赖性TLR信号中，大 …

The newest installment in the ‘Monster’ franchise reveals the true story of the Wichita, Kansas serial killer who murdered at least 10 people between 1974 and 1991. Known by the moniker, BTK – Bind Torture Kill, his notoriety was bolstered by the taunting letters he sent to police, and the chilling phone calls he made to media outlets.