2016年11月30日 · Here, we describe methodologies pertaining to a well-characterized model of cancer cachexia: mice bearing the C26 carcinoma 2-4. Although this model is heavily used in …

C26 tumor-bearing mice are a commonly used experimental model of cancer cachexia 22-24. This model closely resembles the human disease, showing reductions in body, muscle, and fat …

2024年11月1日 · The animal model of C26 cachexia is modeled by subcutaneous inoculation of C26 cells into BALB/c mice unilaterally at a typical inoculation rate of 5 × 10 5 –1 × 10 6 cells …

2021年11月13日 · In this paper, we first screened 23 different syngeneic tumor models treated with anti-PD-1 and found that two colorectal carcinoma CT-26 and Colon 26 tumor models …

2024年12月26日 · We established a cachexia model in BALB/c mice by transplanting C26 cells and administering 5-Aza on day 6 post-transplantation (Figure 3A). Treatment with 5-Aza …

In a syngeneic CT26 model, cancer cells from a particular mouse strain are implanted back into mice of the same strain, allowing researchers to study the interaction between the tumor and …

2021年6月26日 · In our study, the transcriptome of the cachectic gastrocnemius muscle in the C26 xenograft model was integrated and compared with that of 5 more different datasets. The …

动物模型是深入研究cc的重要前提。目前荷c26 小鼠被认为是研究cc最为理想的动物模型，但荷 瘤小鼠进入恶病质不同阶段的判定标准仍有争议， 且在荷瘤小鼠恶病质整个自然发展过程方面 …

2010年7月8日 · Mice bearing ectopically-implanted C26 colon carcinoma are widely used as an experimental model of cancer cachexia. As part of the search for novel clinical and basic …

2019年7月24日 · Cancer cachexia was induced in male BALB/c mice by inoculation of mouse C26 colon adenocarcinoma cells, whereas spleen deficiency syndrome was induced by …

2016年11月30日 · Mice bearing the Colon-26 (C26) carcinoma represent a classical model of cancer cachexia. Progressive muscle wasting occurs in association with tumor growth, over …

2021年11月13日 · Results: We performed in vivo screening for anti-PD-1 therapy across 23 syngeneic tumor models and found that CT-26 and Colon 26, which are murine colorectal …

我们在 23 个同基因肿瘤模型中进行了抗 PD-1 治疗的体内筛选，发现 CT-26 和结肠 26 是源自 BALB/c 小鼠的小鼠结肠直肠癌，对抗 PD-1 显示出不同的敏感性。 CT-26 肿瘤小鼠对抗 PD-1 …

2019年2月21日 · The C26 model was established by subcutaneous injection of 2 × 10 5 C26 cells into the right hind leg. Two different animal experiments were conducted: Firstly, a cachexia …

In this paper, we first screened 23 different syngeneic tumor models treated with anti-PD-1 and found that two colorectal carcinoma CT-26 and Colon 26 tumor models shared similar genetic …

CT26 is an N-nitroso-N-methylurethane- (NNMU) induced, undifferentiated colon carcinoma cell line. It was cloned to generate the cell line designated CT26.WT (ATCC CRL-2638). Use …

2017年3月1日 · We assessed thrombin generation and coagulation parameters in cachectic C26 tumor‐bearing mice. C26 mice are hypercoagulable, partially corrected by blocking tumor …

The present study aimed to determine the impact of colon 26 adenocarcinoma (C26)-induced cancer cachexia on skeletal muscle mitochondrial respiration and content. Twelve male …

2022年3月5日 · The biodistribution and antitumor efficacy of commercially available doxorubicin (DXR)-containing PEGylated liposomes, Doxil®, were scrutinized in the anti-PEG IgM mouse …

CT-26 is a well established model for the study of physiopathology of colon cancers in humans. We have profiled the tumorigenicity of CT-26 mouse colon carcinoma as a flank model in …